Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | TSHR | P16473 | 4/20 | 0.65 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.63 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.63 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | PTPRC | P08575 | 1/20 | 0.50 |
| ▸ | S100A4 | P26447 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29809877 | 1.00 | TDP1 (0.68) | TDP1ALDH1A1TSHRGPR35MAPK1 | |
| SCHEMBL27789642 | 0.89 | TDP1 (0.57) | TDP1ALDH1A1TSHRGPR35MAPK1 | |
| Phenol SCHEMBL28306975 | 0.84 | ALDH1A1 (0.59) | TDP1ALDH1A1TSHRGPR35MAPK1 | |
| SCHEMBL5958796 | 0.83 | TDP1 (0.65) | TDP1ALDH1A1TSHRGPR35MAPK1 | |
| Dinitrochlorobenzene SCHEMBL8970951 | 0.82 | TSHR (0.58) | TDP1ALDH1A1TSHRGPR35MAPK1 | |
| SCHEMBL33520 | 0.81 | TDP1 (1.00) | TDP1ALDH1A1TSHRGPR35MAPK1 | |
| SCHEMBL612437 | 0.81 | TDP1 (0.63) | TDP1ALDH1A1TSHRGPR35MAPK1 | |
| SCHEMBL30293804 | 0.81 | TDP1 (1.00) | TDP1ALDH1A1TSHRGPR35MAPK1 | |
| SCHEMBL3074528 | 0.79 | GPR35 (0.59) | TDP1ALDH1A1TSHRGPR35MAPK1 | |
| SCHEMBL1040777 | 0.79 | GPR35 (1.00) | TDP1ALDH1A1TSHRGPR35MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110713454-A | Nitro-substituted indole compound and preparation method thereof | 南京工业大学 | 2020-01-21 | — | — | CN | claimed |
| CN-107987804-A | A kind of antifreeze conductive fluid of wind-powered electricity generation and preparation method thereof | 中国石油化工股份有限公司 | 2018-05-04 | — | — | CN | claimed |
| US-9127025-B2 | Zn5(BTA)6(TDA)2—a robust highly interpenetrated metal-organic framework constructed from pentanuclear clusters for selective sorption of gas molecules | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-09-08 | — | — | US | claimed |
| US-8507406-B2 | Zn4(OH)2(1,2,4-BTC)2—a rod packing microporous metal-organic framework with open metal sites for selective separation and sensing of small molecules | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-08-13 | — | — | US | claimed |
| US-20130043407-A1 | Zn5(BTA)6(TDA)2 - A ROBUST HIGHLY INTERPENETRATED METAL-ORGANIC FRAMEWORK CONSTRUCTED FROM PENTANUCLEAR CLUSTERS FOR SELECTIVE SORPTION OF GAS MOLECULES | NATIONAL SCIENCE FOUNDATION | 2013-02-21 | — | — | US | claimed |
| US-20120040471-A1 | Zn4(OH)2(1,2,4-BTC)2 - a rod packing microporous metal-organic framework with open metal sites for selective separation and sensing of small molecules | NATIONAL SCIENCE FOUNDATION | 2012-02-16 | — | — | US | claimed |
| CN-117680176-A | Carbon dioxide reduction composite photocatalytic material, preparation method and application | 中国石油化工股份有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-114315636-B | Synthesis method of 1-propyl- [4- (4' -butylphenylazo) ] azobenzene | 烟台丰鲁精细化工有限责任公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-114149385-B | Synthesis method of 1-pyrrolidinyl- (4- (4' -butylphenylazo)) azobenzene | 烟台丰鲁精细化工有限责任公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-111217722-B | Azo aryl urea derivative, and preparation method and application thereof | 华东理工大学 | 2024-01-02 | — | — | CN | disclosed |
| CN-110869552-B | Carpet backing layer composition | 塔吉特GDL公司 | 2022-08-02 | — | — | CN | disclosed |
| US-20220023829-A1 | AMORPHOUS METAL ORGANIC FRAMEWORKS AND METHODS OF PREPARING THE SAME | ABSORPTION SOLUTIONS LLC | 2022-01-27 | — | — | US | disclosed |
| EP-3890878-A2 | AMORPHOUS METAL ORGANIC FRAMEWORKS AND METHODS OF PREPARING THE SAME | Framergy Inc. (US) | 2021-10-13 | — | — | EP | disclosed |
| US-4384983-A | Catalyst and process for production of polyolefins of improved morphology | STANDARD OIL COMPANY (INDIANA) (US) | 1983-05-24 | — | — | US | disclosed |
| EP-0078709-A2 | Preparation of nitroaralkyl cyanides and derivatives thereof | ETHYL CORPORATION (US) | 1983-05-11 | — | — | EP | disclosed |
| EP-0077662-A1 | Preparation of nitroarylacetic acid esters and derivatives thereof | ETHYL CORPORATION (US) | 1983-04-27 | — | — | EP | disclosed |
| US-4370398-A | Electrostatic copying process | RICOH COMPANY, LTD. (JP) | 1983-01-25 | — | — | US | disclosed |
| US-4361638-A | AMORPHOUS SILICON AND CARBON BASE MATERIAL DOPED WITH HYDROGEN AND FLUORINE | FUJI PHOTO FILM CO., LTD. (JP) | 1982-11-30 | — | — | US | disclosed |
| US-4323515-A | Process for the preparation of organic isocyanates from nitro derivatives | P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1982-04-06 | — | — | US | disclosed |
| US-3969413-A | Hydroformylation process using catalyst comprising cobalt and polynitroaryl compounds | UNIVERSAL OIL PRODUCTS COMPANY (US) | 1976-07-13 | — | — | US | disclosed |