Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31456354 | 0.92 | HTR2A (0.37) | ALDH1A1HSD17B10HPGDCYP1A2CYP3A4 | |
| SCHEMBL31212132 | 0.89 | OTUD7B (0.40) | CYP1A2CYP3A4OTUD7BCYP2C19KMT2A | |
| SCHEMBL18181144 | 0.89 | OTUD7B (0.40) | CYP1A2CYP3A4OTUD7BCYP2C19KMT2A | |
| SCHEMBL25275576 | 0.86 | MAP4K1 (0.38) | CYP1A2CYP3A4OTUD7BMAPK1SMN1; SMN2 | |
| SCHEMBL26167986 | 0.86 | MAP4K1 (0.38) | CYP1A2CYP3A4OTUD7BSMN1; SMN2HTR2A | |
| SCHEMBL31456439 | 0.86 | MAP4K1 (0.38) | CYP1A2CYP3A4OTUD7BSMN1; SMN2HTR2A | |
| SCHEMBL29386972 | 0.86 | MAP4K1 (0.38) | CYP1A2CYP3A4OTUD7BMAPK1SMN1; SMN2 | |
| SCHEMBL31456368 | 0.82 | HTR2A (0.40) | ALDH1A1HSD17B10HPGDCYP1A2CYP3A4 | |
| SCHEMBL7572479 | 0.80 | CYP1A2 (0.33) | ALDH1A1HSD17B10HPGDCYP1A2OTUD7B | |
| SCHEMBL20066175 | 0.80 | OTUD7B (0.40) | CYP1A2CYP3A4OTUD7BCYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12208088-B2 | Spirocyclic 2,3-dihydro-7-azaindole compounds and uses thereof | GENENTECH, INC. (US) | 2025-01-28 | — | — | US | claimed |
| EP-1694677-A1 | SPIROPIPERIDINE DERIVATIVES FOR CONTROLLING PESTS | Syngenta Participations AG (CH) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005061500-A1 | SPIROPIPERIDINE DERIVATIVES FOR CONTROLLING PESTS | SYNGENTA PARTICIPATIONS AG (CH) | 2005-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12208088-B2 | Spirocyclic 2,3-dihydro-7-azaindole compounds and uses thereof | HIPK1, NEK1, HIPK2 | ALDH1A1 2398/4885HSD17B10 658/4885HPGD 222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.