Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | BAX | Q07812 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylether SCHEMBL2461810 | 0.78 | LTA4H (1.00) | LTA4HTSHRCA1CA2GSTP1 | |
| Diphenylether SCHEMBL4950525 | 0.78 | LTA4H (1.00) | LTA4HTSHRCA1CA2GSTP1 | |
| Diphenylether SCHEMBL12286 | 0.78 | LTA4H (1.00) | LTA4HTSHRCA1CA2GSTP1 | |
| Diphenylether SCHEMBL9061108 | 0.78 | LTA4H (1.00) | LTA4HTSHRCA1CA2GSTP1 | |
| Diphenylether SCHEMBL22204373 | 0.75 | LTA4H (0.80) | LTA4HTSHRMGLLCA1CA2 | |
| Diphenylether SCHEMBL1566663 | 0.75 | LTA4H (0.80) | LTA4HTSHRMGLLCA1CA2 | |
| Diphenylether SCHEMBL29009484 | 0.75 | LTA4H (0.80) | LTA4HTSHRCA1CA2GSTP1 | |
| Diphenylether SCHEMBL18096784 | 0.74 | LTA4H (0.92) | LTA4HTSHRCA1CA2GSTP1 | |
| Diphenylether SCHEMBL989476 | 0.74 | LTA4H (0.92) | LTA4HTSHRCA1CA2GSTP1 | |
| Diphenylether SCHEMBL6889917 | 0.74 | LTA4H (0.92) | LTA4HTSHRCA1CA2GSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6660820-B1 | Polymeric reaction product of the new class of fluorinated aryl acetylenes, a diphenyloxide biscyclopentadienone and, optionally, 1,3,5-tris(phenylacetylene)benzene | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2003-12-09 | — | — | US | claimed |
| US-20060252906-A1 | Method of synthesis of polyarylenes and the polyarylenes made by such method | GODSCHALX JAMES P | 2006-11-09 | — | — | US | disclosed |
| WO-2004073824-A2 | METHOD OF SYNTHESIS OF POLYARYLENES AND THE POLYARYLENES MADE BY SUCH METHOD | DOW GLOBAL TECHNOLOGIES INC. (US) | 2004-09-02 | — | — | WO | disclosed |
| US-6660820-B1 | Polymeric reaction product of the new class of fluorinated aryl acetylenes, a diphenyloxide biscyclopentadienone and, optionally, 1,3,5-tris(phenylacetylene)benzene | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2003-12-09 | — | — | US | disclosed |
| US-6660820-B1 | Polymeric reaction product of the new class of fluorinated aryl acetylenes, a diphenyloxide biscyclopentadienone and, optionally, 1,3,5-tris(phenylacetylene)benzene | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2003-12-09 | — | — | US | disclosed |