SCHEMBL8529323

SCHEMBL8529323

CN(C)C(=O)C1CC(S)CN1C(=O)O

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3627741 1.00 ATM (0.30) ATM
SCHEMBL8843122 1.00 ATM (0.30) ATM
SCHEMBL15715857 0.80
SCHEMBL5068787 0.80 ATM (0.50) ATM
SCHEMBL5065994 0.80 ATM (0.50) ATM
SCHEMBL6002159 0.80 ATM (0.50) ATM
SCHEMBL2498387 0.80 ATM (0.50) ATM
SCHEMBL20973270 0.80 ATM (0.50) ATM
SCHEMBL25364067 0.79 ATM (0.42) ATM
SCHEMBL6002006 0.79 DPP4 (0.34) ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0504612-B1 Novel 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them AMERICAN CYANAMID CO (US) 1998-01-21 EP disclosed
EP-0504612-A2 Novel 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them AMERICAN CYANAMID COMPANY (US) 1992-09-23 EP disclosed