Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | MLYCD | O95822 | 3/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLQ | O75417 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002629 | 0.70 | NPSR1 (0.34) | NPSR1NR1H3CES1MLYCDNR1H2 | |
| SCHEMBL1008397 | 0.70 | NPSR1 (0.44) | NPSR1NR1H3CES1MLYCDKMT2A | |
| SCHEMBL3938034 | 0.68 | NPSR1 (0.43) | NPSR1NR1H3CES1MLYCDNR1H2 | |
| SCHEMBL6002979 | 0.68 | ELANE (0.32) | NPSR1NR1H3NR1H2KMT2AMEN1 | |
| SCHEMBL11370851 | 0.67 | NPSR1 (0.41) | NPSR1NR1H3CES1MLYCDKMT2A | |
| SCHEMBL28247945 | 0.67 | NPSR1 (0.41) | NPSR1NR1H3CES1MLYCDKMT2A | |
| SCHEMBL7827701 | 0.67 | NPSR1 (0.41) | NPSR1NR1H3CES1MLYCDKMT2A | |
| SCHEMBL1067570 | 0.67 | NPSR1 (0.41) | NPSR1NR1H3CES1MLYCDKMT2A | |
| SCHEMBL9770531 | 0.66 | NR1H3 (0.49) | NPSR1NR1H3MLYCDNR1H2KMT2A | |
| SCHEMBL530567 | 0.65 | MLYCD (0.49) | NPSR1NR1H3CES1MLYCDNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |