Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | TACR1 | P25103 | 2/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.31 |
| ▸ | MLYCD | O95822 | 2/20 | 0.31 |
| ▸ | POLQ | O75417 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002564 | 0.83 | ATM (0.33) | NPSR1NR1H3ATMTDP1L3MBTL1 | |
| SCHEMBL6002568 | 0.71 | TACR1 (0.30) | TACR1 | |
| SCHEMBL6002270 | 0.70 | NPSR1 (0.38) | NPSR1NR1H3CES1TACR1NR1H2 | |
| SCHEMBL5170181 | 0.69 | NPSR1 (0.40) | NPSR1NR1H3ATMTDP1L3MBTL1 | |
| SCHEMBL4131826 | 0.69 | NPSR1 (0.43) | NPSR1ATMTDP1L3MBTL1KMT2A | |
| SCHEMBL5932403 | 0.68 | ALDH1A1 (0.46) | NPSR1L3MBTL1KMT2AMEN1CYP3A4 | |
| SCHEMBL8084617 | 0.67 | CES1 (0.39) | NPSR1NR1H3ATMTDP1L3MBTL1 | |
| SCHEMBL6012131 | 0.67 | NPSR1 (0.38) | NPSR1NR1H3ATMTDP1L3MBTL1 | |
| SCHEMBL17681664 | 0.67 | KMT2A (0.38) | NPSR1NR1H3ATMTDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL27617832 | 0.66 | PDK1 (0.38) | NPSR1NR1H3L3MBTL1TACR1NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |