Toluene

Toluene

SCHEMBL600230

Cc1ccccc1.Cc1ccccc1.Fc1c(F)c(F)c([Ni]c2c(F)c(F)c(F)c(F)c2F)c(F)c1F

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 6/20 0.52
LMNA P02545 2/20 0.52
TSHR P16473 1/20 0.52
ALOX12 P18054 1/20 0.52
HPGD P15428 1/20 0.34
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
NFE2L2 Q16236 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
SMN1; SMN2 Q16637 3/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
HCRTR1 O43613 1/20 0.31
MAPT P10636 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL378637 1.00 ACHE (0.52) ACHELMNATSHRALOX12HPGD
Benzene SCHEMBL378666 0.82
SCHEMBL378833 0.77 ALDH1A1 (0.36) ACHETSHRALDH1A1MEN1KMT2A
Toluene SCHEMBL2286883 0.73 ACHE (0.55) ACHELMNATSHRALOX12HPGD
Toluene SCHEMBL4535818 0.72 ACHE (1.00) ACHELMNATSHRALOX12HPGD
Toluene SCHEMBL8824270 0.72 ACHE (1.00) ACHELMNATSHRALOX12HPGD
SCHEMBL12344943 0.72 ACHE (1.00) ACHELMNATSHRALOX12HPGD
Toluene SCHEMBL4429042 0.72 ACHE (1.00) ACHELMNATSHRALOX12HPGD
Toluene SCHEMBL175861 0.72 ACHE (1.00) ACHELMNATSHRALOX12HPGD
Toluene SCHEMBL8938900 0.72 ACHE (1.00) ACHELMNATSHRALOX12HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9696623-B2 Photosensitive compositions and applications thereof PROMERUS, LLC (US) 2017-07-04 US disclosed
US-9562124-B2 Thermo-oxidatively stable, side chain polyether functionalized polynorbornenes for microelectronic and optoelectronic devices and assemblies thereof PROMERUS, LLC (US) 2017-02-07 US disclosed
US-20160319060-A1 Thermo-oxidatively Stable, Side Chain Polyether Functionalized Polynorbornenes for Microelectronic and Optoelectronic Devices and Assemblies Thereof PROMERUS, LLC (US) 2016-11-03 US disclosed
US-9425404-B2 Thermo-oxidatively stable, side chain polyether functionalized polynorbornenes for microelectronic and optoelectronic devices and assemblies thereof PROMERUS, LLC (US) 2016-08-23 US disclosed
US-20160223908-A1 PHOTOSENSITIVE COMPOSITIONS AND APPLICATIONS THEREOF PROMERUS, LLC (US) 2016-08-04 US disclosed
US-9341949-B2 Photosensitive compositions and applications thereof PROMERUS, LLC (US) 2016-05-17 US disclosed
US-9263416-B2 Methods and materials useful for chip stacking, chip and wafer bonding SUMITOMO BAKELITE CO., LTD. (JP) 2016-02-16 US disclosed
US-8986923-B2 Aqueous base-developable negative-tone films based on functionalized norbornene polymers PROMERUS, LLC (US) 2015-03-24 US disclosed
US-20140349446-A1 METHODS AND MATERIALS USEFUL FOR CHIP STACKING, CHIP AND WAFER BONDING PROMERUS, LLC (US) 2014-11-27 US disclosed
US-20140322647-A1 PHOTOSENSITIVE COMPOSITIONS AND APPLICATIONS THEREOF SUMITOMO BAKELITE CO., LTD (JP) 2014-10-30 US disclosed
EP-1801872-A1 SEMICONDUCTOR DEVICE Sumitomo Bakelite Company, Limited (JP) 2007-06-27 EP disclosed
EP-1771491-A1 PHOTOSENSITIVE COMPOSITIONS BASED ON POLYCYCLIC POLYMERS Promerus, LLC (US) 2007-04-11 EP disclosed
US-20060228562-A1 Semiconductor device, resin composition for buffer coating, resin composition for die bonding, and resin composition for encapsulating SUMITOMO BAKELITE COMPANY LIMITED (JP) 2006-10-12 US disclosed
US-20060167197-A1 Photosensitive compositions based on polycyclic polymers SUMITOMO BAKELITE COMPANY, LTD. (JP) 2006-07-27 US disclosed
US-7022790-B2 Photosensitive compositions based on polycyclic polymers SUMITOMO BAKELITE COMPANY, LTD. (JP) 2006-04-04 US disclosed
WO-2006016925-A1 PHOTOSENSITIVE COMPOSITIONS BASED ON POLYCYCLIC POLYMERS PROMERUS LLC (US) 2006-02-16 WO disclosed
US-20060020068-A1 Photosensitive compositions based on polycyclic polymers for low stress, high temperature films PROMERUS, LLC 2006-01-26 US disclosed
EP-1532486-A1 PHOTOSENSITIVE COMPOSITIONS BASED ON POLYCYCLIC POLYMERS SUMITOMO BAKELITE CO., LTD. (JP) 2005-05-25 EP disclosed
US-20040039153-A1 Photosensitive compositions based on polycyclic polymers SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-02-26 US disclosed
WO-2004006020-A1 PHOTOSENSITIVE COMPOSITIONS BASED ON POLYCYCLIC POLYMERS SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-01-15 WO disclosed