Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2096793 | 0.86 | ALDH1A1 (0.31) | — | |
| SCHEMBL28256785 | 0.83 | ELANE (0.36) | ELANE | |
| SCHEMBL8846995 | 0.75 | MAPT (0.35) | ELANE | |
| SCHEMBL2048302 | 0.75 | ALDH1A1 (0.43) | — | |
| SCHEMBL13615442 | 0.74 | KCNN4 (0.37) | ELANE | |
| SCHEMBL28730692 | 0.73 | LMNA (0.39) | ELANE | |
| SCHEMBL6003031 | 0.73 | ELANE (0.35) | ELANE | |
| SCHEMBL6279751 | 0.73 | SMN1; SMN2 (0.39) | ELANE | |
| SCHEMBL6265278 | 0.73 | ALDH1A1 (0.48) | ELANE | |
| SCHEMBL18242624 | 0.73 | ELANE (0.32) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |