Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3313831 | 0.79 | HDAC6 (0.35) | LOXL2 | |
| SCHEMBL9600991 | 0.75 | — | — | |
| SCHEMBL16048100 | 0.72 | STS (0.31) | STSTLR8 | |
| SCHEMBL496066 | 0.72 | CYP1A2 (0.31) | ALOX15 | |
| SCHEMBL16049260 | 0.71 | STS (0.30) | STS | |
| SCHEMBL6013090 | 0.71 | LOXL2 (0.60) | TLR8LOXL2 | |
| SCHEMBL3315549 | 0.68 | — | — | |
| SCHEMBL16047680 | 0.68 | LOXL2 (0.31) | LOXL2 | |
| SCHEMBL3307999 | 0.66 | EPHX2 (0.34) | — | |
| SCHEMBL3715533 | 0.66 | PPARG (0.69) | STSPPARGALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |