Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001767 | 0.82 | TSHR (0.44) | TSHRALDH1A1HPGDCNR2PPARG | |
| SCHEMBL7094632 | 0.79 | TSHR (0.52) | TSHRALDH1A1HPGDCNR2GAA | |
| SCHEMBL4837680 | 0.78 | TSHR (0.53) | TSHRALDH1A1HPGDCNR2GAA | |
| SCHEMBL12255638 | 0.75 | TSHR (0.56) | TSHRALDH1A1HPGDCNR2GAA | |
| SCHEMBL13443168 | 0.72 | TSHR (0.56) | TSHRALDH1A1PPARGLMNAL3MBTL1 | |
| SCHEMBL1558841 | 0.72 | ALDH1A1 (0.51) | TSHRALDH1A1HPGDGAAPOLB | |
| SCHEMBL23310433 | 0.71 | TSHR (0.54) | TSHRALDH1A1PPARGLMNAL3MBTL1 | |
| SCHEMBL28346434 | 0.71 | ALDH1A1 (0.46) | TSHRALDH1A1HPGDPPARGGAA | |
| SCHEMBL3595029 | 0.70 | CYP4A11 (0.48) | TSHRALDH1A1HPGDGAAPOLB | |
| SCHEMBL31136200 | 0.69 | TSHR (0.72) | TSHRALDH1A1HPGDGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1655280-A1 | Dicarboxylic acid derivates with pharmaceutical properties | Bayer HealthCare AG (DE) | 2006-05-10 | — | — | EP | disclosed |