Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2090980 | 0.84 | KMT2A (0.64) | KMT2AEPHX2L3MBTL1LMNATRPV1 | |
| SCHEMBL8858784 | 0.78 | KMT2A (0.73) | KMT2AEPHX2L3MBTL1LMNATRPV1 | |
| SCHEMBL8858788 | 0.78 | KMT2A (0.73) | KMT2AEPHX2L3MBTL1LMNATRPV1 | |
| SCHEMBL9379470 | 0.78 | POLB (0.65) | KMT2AEPHX2L3MBTL1POLBLMNA | |
| SCHEMBL2056317 | 0.77 | EPHX2 (0.67) | KMT2AEPHX2L3MBTL1POLBLMNA | |
| SCHEMBL30459766 | 0.77 | KMT2A (0.68) | KMT2AEPHX2LMNATRPV1ALDH1A1 | |
| SCHEMBL4117918 | 0.77 | EPHX2 (0.76) | KMT2AEPHX2L3MBTL1POLBLMNA | |
| SCHEMBL23169590 | 0.75 | EPHX2 (0.59) | KMT2AEPHX2L3MBTL1POLBLMNA | |
| SCHEMBL28965383 | 0.75 | MAPT (0.66) | KMT2AEPHX2L3MBTL1POLBLMNA | |
| SCHEMBL6002399 | 0.75 | ALDH1A1 (0.64) | KMT2AEPHX2L3MBTL1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |