Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 5/20 | 0.49 |
| ▸ | CA2 | P00918 | 5/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 5/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5823861 | 1.00 | PTGS2 (0.50) | PTGS2PTGS1CA1CA2CA12 | |
| SCHEMBL7504997 | 0.91 | PTGS2 (0.63) | PTGS2PTGS1CA1CA2CA12 | |
| SCHEMBL6000535 | 0.89 | PTGS2 (0.63) | PTGS2PTGS1NR4A2RXRALMNA | |
| SCHEMBL8550926 | 0.88 | PTGS2 (0.52) | PTGS2PTGS1CA1CA2CA12 | |
| SCHEMBL1534075 | 0.87 | NR4A2 (0.59) | PTGS2PTGS1NR4A2RXRALMNA | |
| SCHEMBL8148150 | 0.86 | CA2 (0.49) | PTGS2PTGS1CA1CA2CA12 | |
| SCHEMBL8147641 | 0.85 | PTGS2 (0.48) | PTGS2PTGS1CA1CA2CA12 | |
| SCHEMBL6002048 | 0.85 | PTGS2 (0.50) | PTGS2PTGS1CA1CA2CA12 | |
| SCHEMBL6002489 | 0.85 | PTGS2 (0.50) | PTGS2PTGS1CA1CA2CA12 | |
| SCHEMBL9428091 | 0.84 | NR4A2 (0.53) | PTGS2PTGS1NR4A2RXRALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060229347-A1 | Treatment of eczemas | ASTION DEVELOPMENT A/S | 2006-10-12 | — | — | US | claimed |
| US-20060229347-A1 | Treatment of eczemas | ASTION DEVELOPMENT A/S | 2006-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060229347-A1 | Treatment of eczemas | ZAP70, SYK, LCK | PTGS2 792/4885PTGS1 745/4885CA1 3406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.