Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | METAP2 | P50579 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1376988 | 0.82 | RAB9A (0.56) | RAB9ALMNANPC1METAP2ALDH1A1 | |
| SCHEMBL31627176 | 0.81 | RAB9A (0.64) | RAB9ALMNANPC1METAP2ALDH1A1 | |
| SCHEMBL1376440 | 0.81 | RAB9A (0.64) | RAB9ALMNANPC1METAP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4270888 | 0.80 | RAB9A (0.62) | RAB9ALMNANPC1METAP2ALDH1A1 | |
| SCHEMBL6015597 | 0.78 | CYP1A2 (0.46) | RAB9ALMNANPC1ALDH1A1PKM | |
| SCHEMBL1375803 | 0.78 | RAB9A (0.60) | RAB9ALMNANPC1METAP2ALDH1A1 | |
| SCHEMBL1378355 | 0.77 | NPC1 (0.78) | RAB9ALMNANPC1METAP2CYP1A2 | |
| SCHEMBL1528569 | 0.77 | NPC1 (1.00) | RAB9ALMNANPC1METAP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4270262 | 0.76 | NPC1 (0.77) | RAB9ALMNANPC1METAP2CYP1A2 | |
| SCHEMBL14791318 | 0.76 | RAB9A (0.55) | RAB9ALMNANPC1METAP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8968708-B2 | Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions | SENOMYX, INC. (US) | 2015-03-03 | — | — | US | disclosed |
| US-8968708-B2 | Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions | SENOMYX, INC. (US) | 2015-03-03 | — | — | US | disclosed |
| US-8968708-B2 | Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions | SENOMYX, INC. (US) | 2015-03-03 | — | — | US | disclosed |
| US-8784782-B2 | Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions | SENOMYX, INC. (US) | 2014-07-22 | — | — | US | disclosed |
| US-8784782-B2 | Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions | SENOMYX, INC. (US) | 2014-07-22 | — | — | US | disclosed |
| US-20130071536-A1 | COMPOUNDS COMPRISING LINKED HETEROARYL MOIETIES AND THEIR USE AS NOVEL UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS FOR COMESTIBLE COMPOSITIONS | SENOMYX, INC. (US) | 2013-03-21 | — | — | US | disclosed |
| US-20130071536-A1 | COMPOUNDS COMPRISING LINKED HETEROARYL MOIETIES AND THEIR USE AS NOVEL UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS FOR COMESTIBLE COMPOSITIONS | SENOMYX, INC. (US) | 2013-03-21 | — | — | US | disclosed |
| US-20060263411-A1 | Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions | SENOMYX, INC. | 2006-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060263411-A1 | Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions | TAS2R46, TAS2R30, TAS2R50 | RAB9A 783/4885LMNA 2666/4885NPC1 3581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.