Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | METAP2 | P50579 | 6/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GRK6 | P43250 | 2/20 | 0.46 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31627176 | 1.00 | RAB9A (0.64) | RAB9ALMNANPC1METAP2CYP1A2 | |
| Hydrochloric Acid SCHEMBL4270888 | 0.99 | RAB9A (0.62) | RAB9ALMNANPC1METAP2CYP1A2 | |
| SCHEMBL1375803 | 0.88 | RAB9A (0.60) | RAB9ALMNANPC1METAP2CYP1A2 | |
| SCHEMBL1378355 | 0.87 | NPC1 (0.78) | RAB9ALMNANPC1METAP2CYP1A2 | |
| Hydrochloric Acid SCHEMBL4270262 | 0.86 | NPC1 (0.77) | RAB9ALMNANPC1METAP2CYP1A2 | |
| SCHEMBL6002513 | 0.81 | RAB9A (0.62) | RAB9ALMNANPC1METAP2CYP1A2 | |
| SCHEMBL1376988 | 0.78 | RAB9A (0.56) | RAB9ALMNANPC1METAP2CYP1A2 | |
| SCHEMBL1528569 | 0.78 | NPC1 (1.00) | RAB9ALMNANPC1METAP2DCUN1D1 | |
| SCHEMBL6015599 | 0.78 | CYP1A2 (0.56) | RAB9ALMNANPC1METAP2CYP1A2 | |
| SCHEMBL1375843 | 0.76 | NPC1 (0.75) | RAB9ALMNANPC1METAP2DCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8968708-B2 | Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions | SENOMYX, INC. (US) | 2015-03-03 | — | — | US | claimed |
| US-8784782-B2 | Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions | SENOMYX, INC. (US) | 2014-07-22 | — | — | US | claimed |
| US-20130071536-A1 | COMPOUNDS COMPRISING LINKED HETEROARYL MOIETIES AND THEIR USE AS NOVEL UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS FOR COMESTIBLE COMPOSITIONS | SENOMYX, INC. (US) | 2013-03-21 | — | — | US | claimed |
| JP-4734346-B2 | — | — | 2011-07-27 | — | — | JP | claimed |
| US-20090018161-A1 | METHOD FOR PROMOTING GASTROINTESTINAL FUNCTION AND METHOD FOR SCREENING FOR PROMOTER OF GASTROINTESTINAL FUNCTION | AJINOMOTO CO. INC. (JP) | 2009-01-15 | — | — | US | claimed |
| EP-1850681-A2 | COMPOUNDS COMPRISING LINKED HETERO ARYL MOIETIES AND THEIR USE AS NOVEL UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS FOR COMESTIBLE COMPOSITIONS | Senomyx, Inc. (US) | 2007-11-07 | — | — | EP | claimed |
| US-20060263411-A1 | Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions | SENOMYX, INC. | 2006-11-23 | — | — | US | claimed |
| WO-2006084186-A2 | COMPOUNDS COMPRISING LINKED HETERO ARYL MOIETIES AND THEIR USE AS NOVEL UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS FOR COMESTIBLE COMPOSITIONS | SENOMYX, INC. (US) | 2006-08-10 | — | — | WO | claimed |
| US-20170143022-A1 | Compositions Incorporating an Umami Flavor Agent | SENOMYX INC (US) | 2017-05-25 | — | — | US | disclosed |
| US-20170143022-A1 | Compositions Incorporating an Umami Flavor Agent | SENOMYX INC (US) | 2017-05-25 | — | — | US | disclosed |
| US-8968708-B2 | Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions | SENOMYX, INC. (US) | 2015-03-03 | — | — | US | disclosed |
| US-8968708-B2 | Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions | SENOMYX, INC. (US) | 2015-03-03 | — | — | US | disclosed |
| US-8968708-B2 | Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions | SENOMYX, INC. (US) | 2015-03-03 | — | — | US | disclosed |
| US-8784782-B2 | Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions | SENOMYX, INC. (US) | 2014-07-22 | — | — | US | disclosed |
| US-20130071536-A1 | COMPOUNDS COMPRISING LINKED HETEROARYL MOIETIES AND THEIR USE AS NOVEL UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS FOR COMESTIBLE COMPOSITIONS | SENOMYX, INC. (US) | 2013-03-21 | — | — | US | disclosed |
| US-20130071536-A1 | COMPOUNDS COMPRISING LINKED HETEROARYL MOIETIES AND THEIR USE AS NOVEL UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS FOR COMESTIBLE COMPOSITIONS | SENOMYX, INC. (US) | 2013-03-21 | — | — | US | disclosed |
| US-20090018161-A1 | METHOD FOR PROMOTING GASTROINTESTINAL FUNCTION AND METHOD FOR SCREENING FOR PROMOTER OF GASTROINTESTINAL FUNCTION | AJINOMOTO CO. INC. (JP) | 2009-01-15 | — | — | US | disclosed |
| US-20090018161-A1 | METHOD FOR PROMOTING GASTROINTESTINAL FUNCTION AND METHOD FOR SCREENING FOR PROMOTER OF GASTROINTESTINAL FUNCTION | AJINOMOTO CO. INC. (JP) | 2009-01-15 | — | — | US | disclosed |
| US-20090018161-A1 | METHOD FOR PROMOTING GASTROINTESTINAL FUNCTION AND METHOD FOR SCREENING FOR PROMOTER OF GASTROINTESTINAL FUNCTION | AJINOMOTO CO. INC. (JP) | 2009-01-15 | — | — | US | disclosed |
| US-20060263411-A1 | Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions | SENOMYX, INC. | 2006-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018161-A1 | METHOD FOR PROMOTING GASTROINTESTINAL FUNCTION AND METHOD FOR SCREENING FOR PROMOTER OF GASTROINTESTINAL FUNCTION | GIPR, GRPR, CCKBR | RAB9A 2387/4885LMNA 4005/4885NPC1 2598/4885 |
| US-20170143022-A1 | Compositions Incorporating an Umami Flavor Agent | TAS2R8, TAS2R45, TAS2R40 | RAB9A 2752/4885LMNA 2068/4885NPC1 2787/4885 |
| US-20060263411-A1 | Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions | TAS2R46, TAS2R30, TAS2R50 | RAB9A 783/4885LMNA 2666/4885NPC1 3581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.