Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 13/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002542 | 0.73 | LMNA (0.33) | — | |
| SCHEMBL254957 | 0.67 | MAPT (0.56) | ALDH1A1TSHRKDM4ETDP1 | |
| SCHEMBL513288 | 0.66 | GRIN2B (0.50) | SLC6A4ALDH1A1TSHR | |
| SCHEMBL514500 | 0.66 | CA1 (0.58) | TDP1 | |
| SCHEMBL10194679 | 0.65 | SLC6A4 (0.54) | SLC6A4SLC6A3SLC6A2KCNH2KDM1A | |
| SCHEMBL1677166 | 0.65 | SLC6A4 (0.53) | SLC6A4SLC6A3SLC6A2KDM1ARCOR1 | |
| SCHEMBL28510655 | 0.64 | MAPT (0.41) | KCNH2SCN10AALDH1A1TSHRKDM4E | |
| SCHEMBL22815879 | 0.64 | SLC6A4 (0.49) | SLC6A4SLC6A3SLC6A2CTSDBACE1 | |
| SCHEMBL28172966 | 0.64 | SLC6A4 (0.49) | SLC6A4SLC6A3SLC6A2CTSDBACE1 | |
| SCHEMBL155707 | 0.63 | TSHR (0.58) | SLC6A4SLC6A3KDM1ARCOR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |