Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5285392 | 0.76 | TSHR (0.37) | LMNAPOLBOPRM1OPRL1OPRK1 | |
| SCHEMBL6002548 | 0.73 | SLC6A4 (0.47) | — | |
| SCHEMBL5275530 | 0.72 | KDM4E (0.35) | POLBOPRM1OPRL1MEN1KMT2A | |
| SCHEMBL5287640 | 0.72 | POLB (0.41) | LMNAPOLBMEN1KMT2A | |
| SCHEMBL3925565 | 0.71 | GAA (0.41) | LMNAPOLBDPP4OPRM1OPRL1 | |
| SCHEMBL2233425 | 0.71 | MAOA (0.32) | DPP4 | |
| SCHEMBL5275494 | 0.71 | OPRM1 (0.32) | POLBOPRM1OPRL1OPRK1 | |
| SCHEMBL5280180 | 0.71 | ALDH1A1 (0.36) | OPRM1OPRL1OPRK1OPRD1MEN1 | |
| SCHEMBL5282094 | 0.70 | OPRL1 (0.42) | OPRM1OPRL1OPRK1 | |
| SCHEMBL5279220 | 0.69 | OPRM1 (0.44) | OPRM1OPRL1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |