Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3889561 | 0.81 | MEN1 (0.51) | MEN1LMNAKMT2APAX8MAPT | |
| SCHEMBL13836072 | 0.80 | MEN1 (0.41) | MEN1LMNAKMT2APAX8MAPT | |
| SCHEMBL498377 | 0.79 | ALDH1A1 (0.56) | MEN1LMNAKMT2APAX8MAPT | |
| SCHEMBL12015662 | 0.77 | MEN1 (0.50) | MEN1LMNAKMT2APAX8MAPT | |
| SCHEMBL4375292 | 0.77 | ALDH1A1 (0.47) | MEN1LMNAKMT2APAX8MAPT | |
| SCHEMBL2089756 | 0.77 | MAPT (0.53) | MEN1LMNAKMT2AMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28806796 | 0.76 | MEN1 (0.49) | MEN1LMNAKMT2APAX8MAPT | |
| Hydrochloric Acid SCHEMBL10564643 | 0.76 | MEN1 (0.46) | MEN1LMNAKMT2APAX8MAPT | |
| SCHEMBL9069320 | 0.74 | PIK3CD (0.61) | MEN1LMNAKMT2APAX8MAPT | |
| SCHEMBL1119471 | 0.74 | ALDH1A1 (0.47) | MEN1LMNAKMT2APAX8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |