Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10564643 | 0.98 | MEN1 (0.46) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL498377 | 0.82 | ALDH1A1 (0.56) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL12015662 | 0.80 | MEN1 (0.50) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL16792598 | 0.80 | XDH (0.40) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL28806796 | 0.78 | MEN1 (0.49) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL6002583 | 0.77 | MEN1 (0.44) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL3889561 | 0.77 | MEN1 (0.51) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL9069320 | 0.77 | PIK3CD (0.61) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL9682 | 0.77 | MAPT (0.63) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18380932 | 0.76 | SCN5A (0.56) | ALDH1A1MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |
| US-4864032-A | Process for the preparation of indazoles | ORTHO PHARMACEUTICAL CORPORATION | 1989-09-05 | — | — | US | disclosed |