Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2095004 | 0.81 | TRPM8 (0.36) | PARP15PARP10LTA4HSLC6A3TDP1 | |
| SCHEMBL28163849 | 0.74 | — | — | |
| SCHEMBL27548446 | 0.72 | RAB9A (0.36) | PARP15PARP10LTA4HSLC6A3TDP1 | |
| SCHEMBL28905989 | 0.72 | TDP1 (0.44) | PARP15PARP10SLC6A3TDP1RAB9A | |
| Hydrochloric Acid SCHEMBL29290253 | 0.70 | RAB9A (0.35) | PARP15PARP10LTA4HSLC6A3TDP1 | |
| SCHEMBL2092469 | 0.69 | TLR7 (0.39) | PARP15PARP10LTA4HSLC6A3TDP1 | |
| SCHEMBL2474170 | 0.69 | LMNA (0.38) | PARP15PARP10SLC6A3TDP1RAB9A | |
| SCHEMBL17080164 | 0.69 | PARP15 (0.47) | PARP15PARP10SLC6A3TDP1RAB9A | |
| SCHEMBL272570 | 0.69 | — | — | |
| SCHEMBL2472947 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |