SCHEMBL600270

SCHEMBL600270

O=C1OC(=O)c2c1c(O)cc1ccccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM4 Q8TD43 1/20 0.50
ALOX5 P09917 3/20 0.46
NQO2 P16083 1/20 0.44
DAO P14920 2/20 0.43
HPGD P15428 2/20 0.43
TYR P14679 1/20 0.43
AKR1B1 P15121 1/20 0.43
NQO1 P15559 1/20 0.42
DHFR P00374 1/20 0.40
TYMS P04818 1/20 0.40
CES1 P23141 1/20 0.40
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
GPR84 Q9NQS5 3/20 0.39
KDM4E B2RXH2 2/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA9 Q16790 1/20 0.39
DDO Q99489 1/20 0.39
CYP1A2 P05177 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9413380 0.81 CA12 (0.41) KMT2AKDM4ECA12CA1CA9
SCHEMBL10880492 0.78 NQO1 (0.51) TRPM4ALOX5NQO1TYMSCES1
SCHEMBL4957625 0.77 AHR (0.42) ALOX5CES1MEN1KMT2AGPR84
SCHEMBL6289873 0.77 CES1 (0.40) ALOX5HPGDNQO1CES1MEN1
SCHEMBL8735650 0.77 CYP1A2 (0.44) ALOX5HPGDCES1MEN1KMT2A
SCHEMBL9038314 0.77 POLB (0.43) ALOX5HPGDNQO1CES1MEN1
SCHEMBL4961115 0.77 CES1 (0.40) ALOX5HPGDNQO1CES1MEN1
SCHEMBL4960932 0.77 TYMS (0.40) ALOX5DHFRTYMSCES1MEN1
SCHEMBL3967192 0.77 ALDH1A1 (0.40) ALOX5HPGDNQO1CES1MEN1
SCHEMBL5795357 0.77 WDR5 (0.53) HPGDTYMSMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12486362-B2 Polyester polyol comprising an imide moiety and methods of manufacture thereof HUNTSMAN INTERNATIONAL LLC 2025-12-02 US disclosed
US-12252578-B2 Polyurethane foam composition comprising an aromatic polyester polyol compound and products made therefrom HUNTSMAN INTERNATIONAL LLC 2025-03-18 US disclosed
US-20220315705-A1 POLYESTER POLYOL COMPRISING AN IMIDE MOIETY AND METHODS OF MANUFACTURE THEREOF HUNTSMAN INTERNATIONAL LLC 2022-10-06 US disclosed
US-20220275144-A1 POLYURETHANE FOAM COMPOSITION COMPRISING AN AROMATIC POLYESTER POLYOL COMPOUND AND PRODUCTS MADE THEREFROM HUNTSMAN INTERNATIONAL LLC 2022-09-01 US disclosed
EP-4010394-A1 POLYESTER POLYOL COMPRISING AN IMIDE MOIETY AND METHODS OF MANUFACTURE THEREOF Huntsman International LLC (US) 2022-06-15 EP disclosed
EP-4010395-A1 POLYURETHANE FOAM COMPOSITION COMPRISING AN AROMATIC POLYESTER POLYOL COMPOUND AND PRODUCTS MADE THEREFROM Huntsman International LLC (US) 2022-06-15 EP disclosed
CN-114341222-A Polyurethane foam compositions containing aromatic polyester polyol compounds and products made therefrom 亨斯迈国际有限责任公司 2022-04-12 CN disclosed
CN-114286831-A Polyester polyol containing imide moiety and method for preparing the same 亨斯迈国际有限责任公司 2022-04-05 CN disclosed
WO-2021030117-A1 POLYESTER POLYOL COMPRISING AN IMIDE MOIETY AND METHODS OF MANUFACTURE THEREOF HUNTSMAN INTERNATIONAL LLC (US) 2021-02-18 WO disclosed
WO-2021030115-A1 POLYURETHANE FOAM COMPOSITION COMPRISING AN AROMATIC POLYESTER POLYOL COMPOUND AND PRODUCTS MADE THEREFROM HUNTSMAN INTERNATIONAL LLC (US) 2021-02-18 WO disclosed
US-4791194-A DURABILITY; ELECTROGRAPHY MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) 1988-12-13 US disclosed
EP-0291089-A2 Electrophotographic photoreceptor MITSUBISHI KASEI CORPORATION (JP) 1988-11-17 EP disclosed
EP-0150707-B1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI KASEI CORPORATION (JP) 1988-04-13 EP disclosed
US-4618555-A PHOTOSENSITIVITY; DURABILITY MITSUBISHI CHEMICAL IND., LTD. (JP) 1986-10-21 US disclosed
EP-0063387-B1 ELECTROPHOTOGRAPHIC PLATE MITSUBISHI KASEI CORPORATION (JP) 1986-07-23 EP disclosed
US-4578469-A COUMARIN DYES HOECHST AKTIENGESELLSCHAFT (DE) 1986-03-25 US disclosed
EP-0150707-A1 Electrophotographic photoreceptor MITSUBISHI KASEI CORPORATION (JP) 1985-08-07 EP disclosed
US-4396696-A Electrophotographic plate having azo compound photosensitive layer MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1983-08-02 US disclosed
EP-0063387-A1 Electrophotographic plate MITSUBISHI KASEI CORPORATION (JP) 1982-10-27 EP disclosed
US-4002630-A INTERMEDIATES FOR AZO-METHINE DYES HOECHST AKTIENGESELLSCHAFT (DT) 1977-01-11 US disclosed