Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9038314 | 0.77 | POLB (0.43) | CES1ALOX5PTGESKDM4EMEN1 | |
| SCHEMBL3967192 | 0.77 | ALDH1A1 (0.40) | CES1ALOX5PTGESKDM4EMEN1 | |
| SCHEMBL4957625 | 0.77 | AHR (0.42) | CES1ALOX5PTGESKDM4EMEN1 | |
| SCHEMBL4961115 | 0.77 | CES1 (0.40) | CES1ALOX5PTGESKDM4EMEN1 | |
| SCHEMBL8735650 | 0.77 | CYP1A2 (0.44) | CES1ALOX5PTGESKDM4EMEN1 | |
| SCHEMBL600270 | 0.77 | TRPM4 (0.50) | CES1ALOX5KDM4EMEN1KMT2A | |
| SCHEMBL4960932 | 0.77 | TYMS (0.40) | CES1ALOX5PTGESKDM4EMEN1 | |
| SCHEMBL5998049 | 0.74 | GPR84 (0.55) | ALOX5PTGESKDM4EMEN1KMT2A | |
| SCHEMBL11463067 | 0.73 | GPR84 (0.54) | CES1ALOX5KDM4EMEN1KMT2A | |
| SCHEMBL5795357 | 0.73 | WDR5 (0.53) | KDM4EMEN1KMT2AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6939364-B1 | placing tissues in proximity, providing an adhesive with collagen content of 300-800 mg/ml that is gelatinized with thermal energy and derivatized with a carbox group, and exposing to electromagnetic radiation | TISSUE ADHESIVE TECHNOLOGIES, INC. (US) | 2005-09-06 | — | — | US | disclosed |
| US-6875427-B1 | Light energized tissue adhesive | TISSUE ADHESIVE TECHNOLOGIES, INC. (US) | 2005-04-05 | — | — | US | disclosed |
| US-6780840-B1 | Method for making a light energized tissue adhesive | TISSUE ADHESIVE TECHNOLOGIES, INC. | 2004-08-24 | — | — | US | disclosed |
| US-6773699-B1 | Light energized tissue adhesive conformal patch | TISSUE ADHESIVE TECHNOLOGIES, INC. | 2004-08-10 | — | — | US | disclosed |