Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.34 |
| ▸ | LTA4H | P09960 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10557530 | 0.72 | LTA4H (0.57) | LTA4H | |
| SCHEMBL28165298 | 0.70 | SLC6A3 (0.39) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL1429587 | 0.67 | LTA4H (0.56) | LTA4H | |
| SCHEMBL1429585 | 0.67 | LTA4H (0.56) | LTA4H | |
| Hydrochloric Acid SCHEMBL1429371 | 0.66 | LTA4H (0.55) | SLC6A2SLC6A4LTA4H | |
| Hydrochloric Acid SCHEMBL1429369 | 0.66 | LTA4H (0.55) | SLC6A2SLC6A4LTA4H | |
| SCHEMBL6002478 | 0.66 | POLB (0.49) | LTA4HCYP2D6KCNH2 | |
| SCHEMBL1402181 | 0.66 | — | — | |
| SCHEMBL18983085 | 0.64 | CHRNB2 (0.38) | LTA4HCYP2D6 | |
| SCHEMBL3643546 | 0.63 | SLC6A2 (0.41) | SLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |