Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 7/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2091188 | 0.88 | APP (0.35) | HRH3APPRAB9AALDH1A1KMT2A | |
| SCHEMBL27644906 | 0.74 | RAB9A (0.48) | APPRAB9AMEN1KMT2AMAOB | |
| SCHEMBL4806763 | 0.70 | — | — | |
| SCHEMBL2095891 | 0.68 | APP (0.42) | APPRAB9AALDH1A1KMT2AMAOB | |
| SCHEMBL2096161 | 0.68 | APP (0.48) | APPRAB9A | |
| SCHEMBL2097746 | 0.68 | NPC1 (0.48) | APPRAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL2088662 | 0.67 | ALDH1A1 (0.50) | RAB9AALDH1A1MEN1KMT2ALTA4H | |
| SCHEMBL2095579 | 0.67 | SLC6A4 (0.40) | ALDH1A1 | |
| SCHEMBL15082057 | 0.65 | LMNA (0.53) | HRH3APPALDH1A1MEN1KMT2A | |
| SCHEMBL17858378 | 0.65 | HRH3 (0.50) | HRH3APPRAB9ALTA4HSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |