Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.51 |
| ▸ | PPARD | Q03181 | 3/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2097759 | 0.84 | FFAR1 (0.53) | FFAR1PPARDTRPM8SMN1; SMN2L3MBTL1 | |
| SCHEMBL2097756 | 0.83 | FFAR1 (0.52) | FFAR1PPARDTRPM8SMN1; SMN2L3MBTL1 | |
| SCHEMBL6840453 | 0.82 | L3MBTL1 (0.55) | FFAR1PPARDTRPM8SMN1; SMN2L3MBTL1 | |
| SCHEMBL27943053 | 0.81 | LMNA (0.53) | FFAR1PPARDTRPM8SMN1; SMN2MAPT | |
| SCHEMBL7693031 | 0.79 | ALOX5 (0.57) | FFAR1PPARDALOX5SMN1; SMN2NPC1 | |
| Bromobenzene SCHEMBL27953553 | 0.77 | CDC7 (0.46) | FFAR1PPARDTRPM8CDC7DBF4 | |
| Chlorobenzene SCHEMBL27953551 | 0.77 | CDC7 (0.46) | FFAR1PPARDTRPM8CDC7DBF4 | |
| Fluorobenzene SCHEMBL27942966 | 0.77 | CDC7 (0.46) | FFAR1PPARDCDC7DBF4MAPT | |
| SCHEMBL1569202 | 0.77 | SMN1; SMN2 (0.53) | FFAR1PPARDTRPM8SMN1; SMN2L3MBTL1 | |
| SCHEMBL2413521 | 0.77 | SMN1; SMN2 (0.51) | FFAR1PPARDSMN1; SMN2NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |