Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 7/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002777 | 0.98 | FAAH (0.48) | FAAHTRPA1CES1NCEH1S1PR2 | |
| SCHEMBL6000698 | 0.95 | FAAH (0.41) | FAAHTRPA1CES1NCEH1 | |
| SCHEMBL2097333 | 0.83 | CES1 (0.39) | FAAHTRPA1CES1NCEH1S1PR2 | |
| SCHEMBL2095618 | 0.82 | CES1 (0.41) | FAAHTRPA1CES1NCEH1S1PR2 | |
| SCHEMBL2096342 | 0.82 | CES1 (0.41) | FAAHTRPA1CES1NCEH1S1PR2 | |
| SCHEMBL19354261 | 0.82 | IDO1 (0.43) | TRPA1 | |
| SCHEMBL19354535 | 0.82 | IDO1 (0.43) | TRPA1 | |
| SCHEMBL5641256 | 0.81 | MAOA (0.42) | FAAHCES1NCEH1S1PR2S1PR4 | |
| SCHEMBL5642021 | 0.80 | MAOA (0.41) | FAAHTRPA1CES1NCEH1S1PR2 | |
| SCHEMBL2093740 | 0.78 | DAO (0.38) | CES1NCEH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |