Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8055265 | 0.69 | ESR1 (0.39) | ESR1LPLLIPGIMPDH2 | |
| SCHEMBL14763940 | 0.66 | — | — | |
| SCHEMBL2093604 | 0.65 | SLC6A4 (0.33) | ESR1LPLLIPGIMPDH2 | |
| SCHEMBL2010826 | 0.64 | ESR1 (0.39) | ESR1LPLLIPGIMPDH2 | |
| SCHEMBL8040627 | 0.64 | ESR1 (0.35) | ESR1LPLLIPGIMPDH2 | |
| SCHEMBL29181451 | 0.61 | ERN1 (0.34) | ESR1LPLLIPGIMPDH2 | |
| SCHEMBL11483469 | 0.61 | PTGER2 (0.38) | ESR1LPLLIPG | |
| SCHEMBL26260126 | 0.61 | F2 (0.35) | LPLLIPGIMPDH2 | |
| SCHEMBL12591815 | 0.61 | KIF11 (0.48) | LPLLIPG | |
| SCHEMBL6598923 | 0.61 | ESR1 (0.41) | ESR1LPLLIPGIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |