Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 2/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2093686 | 0.85 | PDK1 (0.46) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| SCHEMBL2093688 | 0.83 | ALDH1A1 (0.56) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| SCHEMBL2095525 | 0.80 | PDK1 (0.49) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| SCHEMBL2095523 | 0.80 | PDK1 (0.49) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| SCHEMBL2091972 | 0.78 | MAPT (0.48) | ALDH1A1GAAMAPTHPGDTSHR | |
| SCHEMBL2094340 | 0.78 | MAPT (0.61) | ALDH1A1GAAMAPTTSHRHTT | |
| SCHEMBL2092275 | 0.76 | MEN1 (0.60) | GAAMAPTHPGDTSHRPOLB | |
| SCHEMBL27721938 | 0.76 | MTNR1B (0.59) | ALDH1A1GAAMAPTHPGDALOX15 | |
| SCHEMBL2094765 | 0.73 | ALDH1A1 (0.56) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| SCHEMBL11266669 | 0.73 | MEN1 (0.63) | ALDH1A1MAPTHPGDALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |