Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6003103 | 0.82 | NPC1 (0.57) | NPC1ALDH1A1GLAHTTRAB9A | |
| SCHEMBL1927016 | 0.81 | ALDH1A1 (0.69) | NPC1ALDH1A1GLAHTTRAB9A | |
| SCHEMBL514163 | 0.80 | TSHR (0.63) | ALDH1A1GLAHTTSMN1; SMN2TSHR | |
| SCHEMBL10921379 | 0.79 | ALDH1A1 (0.62) | NPC1ALDH1A1GLAHTTRAB9A | |
| SCHEMBL1925076 | 0.79 | ALDH1A1 (0.59) | NPC1ALDH1A1GLAHTTRAB9A | |
| SCHEMBL11552690 | 0.79 | NPC1 (0.50) | NPC1ALDH1A1GLAHTTRAB9A | |
| SCHEMBL2095207 | 0.76 | NPC1 (0.59) | NPC1ALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL28207526 | 0.76 | CHRM2 (0.52) | NPC1ALDH1A1GLAHTTRAB9A | |
| SCHEMBL5694553 | 0.76 | TSPO (0.72) | NPC1ALDH1A1GLAHTTRAB9A | |
| Carbamic Acid SCHEMBL6468271 | 0.76 | NPC1 (0.62) | NPC1ALDH1A1GLAHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |