SCHEMBL6003149

SCHEMBL6003149

CCc1nc(C)c(CO)[nH]1

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 5/20 0.39
ADORA3 P0DMS8 4/20 0.39
ADORA2A P29274 3/20 0.39
TP53 P04637 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
DDAH1 O94760 1/20 0.34
GAA P10253 1/20 0.32
HTT P42858 1/20 0.32
TNKS2 Q9H2K2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11194272 0.98 ADORA1 (0.38) ADORA1ADORA3ADORA2ATP53L3MBTL1
SCHEMBL10514714 0.86 KDM4E (0.36)
SCHEMBL6855320 0.84 ADORA1 (0.43) ADORA1ADORA3ADORA2ATP53L3MBTL1
SCHEMBL25047048 0.82 L3MBTL1 (0.44) ADORA1ADORA3ADORA2ATP53L3MBTL1
SCHEMBL9271915 0.80 TP53 (0.35) ADORA1ADORA3ADORA2ATP53L3MBTL1
SCHEMBL3703117 0.78 PDK2 (0.40) ADORA1ADORA3ADORA2ATP53L3MBTL1
SCHEMBL4353447 0.78 ADORA1 (0.39) ADORA1ADORA3ADORA2ADDAH1GAA
SCHEMBL7451055 0.78 SMN1; SMN2 (0.37) L3MBTL1
SCHEMBL3027998 0.77 GAA (0.39) ADORA1ADORA3ADORA2ADDAH1GAA
SCHEMBL28831410 0.75 ALDH1A1 (0.37) ADORA1ADORA3ADORA2ATP53L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4663190-A CURING EPOXY RESIN, DIBASIC ACID, IMIDAZOLE HITACHI CHEMICAL COMPANY, LTD. (JP) 1987-05-05 US claimed
JP-59109519-A None JP disclosed
JP-59157110-A None JP disclosed
JP-60053526-A None JP disclosed
CN-115699273-A Adhesive sheet for manufacturing semiconductor device and method for manufacturing semiconductor device using the same 株式会社巴川制纸所 2023-02-03 CN disclosed
CN-100443512-C Thermoplastic elastomer and thermoplastic elastomer composition YOKOHAMA RUBBER CO LTD (JP) 2008-12-17 CN disclosed
US-20060199917-A1 thermoplastic elastomer exhibiting high recyclability and oil resistance as well as excellent mechanical strength, and in particular, excellent resistance to compression set is provided. The thermoplastic resin with epoxy, hydroxy or nitrogen groups in backbone YOKOHAMA RUBBER CO., LTD., THE (JP) 2006-09-07 US disclosed
CN-1738837-A Thermoplastic elastomer and thermoplastic elastomer composition YOKOHAMA RUBBER CO LTD (JP) 2006-02-22 CN disclosed
US-5374646-A Treatment or prophylasix of hypertension and diseases associated with cognitive disorders GLAXO GROUP LIMITED (GB) 1994-12-20 US disclosed
WO-1992020673-A1 ANTIHYPOTENSIVE BENZOFURAN DERIVATIVES WITH N-LINKED 1H-IMIDAZOLYLMETHYL-5-CARBOXAMIDE SUBSTITUENTS GLAXO GROUP LIMITED (GB) 1992-11-26 WO disclosed
EP-0434249-A2 Benzofuran derivatives GLAXO GROUP LIMITED (GB) 1991-06-26 EP disclosed
US-4663190-A CURING EPOXY RESIN, DIBASIC ACID, IMIDAZOLE HITACHI CHEMICAL COMPANY, LTD. (JP) 1987-05-05 US disclosed
JP-S6053526-A EPOXY RESIN COMPOSITION FOR SEALING SEMICONDUCTOR HITACHI CHEM CO LTD 1985-03-27 JP disclosed
JP-S59157110-A PHENOLIC RESIN CONTAINING IMIDAZOLE RING HITACHI LTD 1984-09-06 JP disclosed
JP-S59109519-A PRODUCTION OF SEMICONDUCTOR ELEMENT HITACHI CHEM CO LTD 1984-06-25 JP disclosed
US-4297516-A PROSTAGLANDINS AMERICAN CYANAMID COMPANY (US) 1981-10-27 US disclosed
EP-0006102-B1 1-HYDROXYMETHYLIMIDAZOLES, THEIR PREPARATION AND USE AS CHEMICAL INTERMEDIATES BASF Aktiengesellschaft (DE) 1981-02-11 EP disclosed
US-4242517-A 4-METHYL-1 -HYDROXYMETHYLIMIDAZOLE AND CYSTEAMINE IN BOILING AQUEOUS HYDROCHLORIC ACID BASF AKTIENGESELLSCHAFT (DE) 1980-12-30 US disclosed
US-4239895-A Process for producing 1-hydroxymethylimidazoles BASF AKTIENGESELLSCHAFT (DE) 1980-12-16 US disclosed
EP-0006102-A1 1-Hydroxymethylimidazoles, their preparation and use as chemical intermediates BASF Aktiengesellschaft (DE) 1980-01-09 EP disclosed