Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | EEF2K | O00418 | 1/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | CDC25A | P30304 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19949917 | 0.79 | KDM4E (0.51) | KDM4ELMNAHTR1AMEN1KMT2A | |
| SCHEMBL29531557 | 0.72 | ALDH1A1 (0.70) | KDM4ELMNAHTR1AMEN1KMT2A | |
| SCHEMBL6698921 | 0.72 | ALDH1A1 (0.70) | KDM4ELMNAHTR1AMEN1KMT2A | |
| SCHEMBL4819614 | 0.72 | ADRA2C (0.33) | KDM4EHTR1AMEN1KMT2AALDH1A1 | |
| SCHEMBL11883383 | 0.71 | ADRA1D (0.34) | KDM4ELMNAHTR1AMEN1KMT2A | |
| SCHEMBL25227934 | 0.71 | ALDH1A1 (0.68) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL9549231 | 0.71 | ALDH1A1 (0.68) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL19746738 | 0.71 | ALDH1A1 (0.68) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL8703125 | 0.71 | ALDH1A1 (0.68) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL25229724 | 0.71 | ALDH1A1 (0.68) | KDM4ELMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |