Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | BID | P55957 | 3/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.42 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6542314 | 0.98 | MEN1 (0.43) | ALDH1A1MEN1LMNATHRATHRB | |
| SCHEMBL29356330 | 0.93 | ALDH1A1 (0.44) | ALDH1A1MEN1LMNATHRATHRB | |
| SCHEMBL6256898 | 0.93 | ALDH1A1 (0.44) | ALDH1A1MEN1LMNATHRATHRB | |
| SCHEMBL7470640 | 0.90 | LIPG (0.47) | ALDH1A1LIPGBIDMCL1BCL2L1 | |
| SCHEMBL6241252 | 0.90 | DPP4 (0.41) | ALDH1A1MEN1LMNATHRATHRB | |
| SCHEMBL2094732 | 0.83 | LMNA (0.41) | ALDH1A1MEN1LMNATHRATHRB | |
| SCHEMBL14481405 | 0.82 | LIPG (0.38) | ALDH1A1LIPGBIDMCL1BCL2L1 | |
| SCHEMBL9720039 | 0.82 | BCL2L1 (0.54) | ALDH1A1MEN1LMNATHRATHRB | |
| SCHEMBL2091729 | 0.81 | LMNA (0.40) | ALDH1A1MEN1LMNATHRATHRB | |
| SCHEMBL9115008 | 0.80 | BCL2L1 (0.38) | ALDH1A1MEN1LMNATHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1052982-A4 | AMINOTETRALINS AS 5-HT 1D$g(a)? AGONISTS | LILLY CO ELI (US) | 2004-10-06 | — | — | EP | disclosed |
| EP-1052982-A1 | AMINOTETRALINS AS 5-HT 1D$g(a)? AGONISTS | ELI LILLY AND COMPANY (US) | 2000-11-22 | — | — | EP | disclosed |
| WO-1998048786-A1 | AMINOTETRALINS AS 5-HT1Dα AGONISTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |