Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5243063 | 0.92 | ALDH1A1 (0.74) | TSHRALDH1A1MAPTNPC1KDM4E | |
| SCHEMBL29873927 | 0.84 | ALDH1A1 (0.73) | TSHRALDH1A1NPC1KDM4ELMNA | |
| SCHEMBL5245302 | 0.81 | TSHR (1.00) | TSHRALDH1A1NPC1KDM4ELMNA | |
| SCHEMBL19392388 | 0.81 | MAPT (0.80) | TSHRALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL12793334 | 0.81 | MAPT (0.80) | TSHRALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL25293495 | 0.81 | MAPT (0.80) | TSHRALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL5105726 | 0.79 | GAA (0.61) | TSHRALDH1A1MAPTNPC1KDM4E | |
| SCHEMBL6003302 | 0.79 | TSHR (0.76) | TSHRALDH1A1NPC1KDM4ELMNA | |
| SCHEMBL5243147 | 0.79 | TSHR (0.72) | TSHRALDH1A1NPC1KDM4ELMNA | |
| SCHEMBL7700065 | 0.79 | AKR1C3 (0.66) | ALDH1A1MAPTLMNAHTTAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060199816-A1 | Aryl sulfonyl piperidines | GILLESPIE PAUL | 2006-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199816-A1 | Aryl sulfonyl piperidines | GPR119, SLC5A2, GLS2 | TSHR 761/4885ALDH1A1 88/4885MAPT 4530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.