Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5245302 | 0.86 | TSHR (1.00) | TSHRALDH1A1NPC1EPHX2LMNA | |
| SCHEMBL4006092 | 0.83 | TSHR (0.90) | TSHRALDH1A1NPC1EPHX2LMNA | |
| SCHEMBL4006097 | 0.83 | TSHR (0.90) | TSHRALDH1A1NPC1EPHX2LMNA | |
| SCHEMBL5243063 | 0.81 | ALDH1A1 (0.74) | TSHRALDH1A1NPC1LMNAHTT | |
| SCHEMBL7534615 | 0.81 | ALDH1A1 (1.00) | TSHRALDH1A1NPC1LMNAHTT | |
| SCHEMBL29873927 | 0.80 | ALDH1A1 (0.73) | TSHRALDH1A1NPC1LMNAHTT | |
| SCHEMBL5243147 | 0.79 | TSHR (0.72) | TSHRALDH1A1NPC1LMNAHTT | |
| Cyclohexylamine SCHEMBL6003299 | 0.79 | TSHR (0.69) | TSHRALDH1A1NPC1LMNAHTT | |
| SCHEMBL6323332 | 0.75 | GAA (0.67) | TSHRALDH1A1NPC1LMNAHTT | |
| SCHEMBL608974 | 0.74 | TSHR (0.77) | TSHRALDH1A1NPC1EPHX2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060199816-A1 | Aryl sulfonyl piperidines | GILLESPIE PAUL | 2006-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199816-A1 | Aryl sulfonyl piperidines | GPR119, SLC5A2, GLS2 | TSHR 761/4885ALDH1A1 88/4885NPC1 234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.