SCHEMBL6003472

SCHEMBL6003472

O=Cc1ccccc1-c1ccc(Cl)cc1C=O

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 4/20 0.52
TDP1 Q9NUW8 2/20 0.50
S100A4 P26447 2/20 0.47
MEN1 O00255 1/20 0.46
LMNA P02545 1/20 0.46
THRB P10828 1/20 0.46
BLM P54132 1/20 0.46
KMT2A Q03164 1/20 0.46
XDH P47989 1/20 0.45
GPR3 P46089 1/20 0.41
ALDH1A1 P00352 2/20 0.39
TSHR P16473 1/20 0.39
TRIM24 O15164 1/20 0.39
TRIM33 Q9UPN9 1/20 0.39
MAPT P10636 1/20 0.39
AR P10275 1/20 0.38
PTPN1 P18031 1/20 0.38
EIF4E P06730 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10041701 0.89 TDP1 (0.52) ERN1TDP1S100A4MEN1LMNA
SCHEMBL10041704 0.89 TDP1 (0.57) ERN1TDP1S100A4MEN1LMNA
SCHEMBL6930919 0.88 TDP1 (0.55) ERN1TDP1S100A4MEN1LMNA
SCHEMBL2448925 0.85 ERN1 (0.46) ERN1TDP1S100A4MEN1LMNA
SCHEMBL28533543 0.85 ALDH1A1 (0.47) ERN1TDP1S100A4MEN1LMNA
SCHEMBL26647837 0.85 TDP1 (0.44) ERN1TDP1S100A4MEN1LMNA
SCHEMBL10041658 0.85 TDP1 (0.52) ERN1TDP1S100A4MEN1LMNA
SCHEMBL27547924 0.83 ERN1 (0.47) ERN1TDP1S100A4MEN1LMNA
SCHEMBL14141574 0.83 ERN1 (0.43) ERN1TDP1S100A4MEN1LMNA
SCHEMBL1646527 0.82 XDH (0.55) ERN1TDP1S100A4MEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8729541-B2 Phenanthrene compound and organic light emitting device using the same CANON KABUSHIKI KAISHA (JP) 2014-05-20 US disclosed
US-8729541-B2 Phenanthrene compound and organic light emitting device using the same CANON KABUSHIKI KAISHA (JP) 2014-05-20 US disclosed
US-8729541-B2 Phenanthrene compound and organic light emitting device using the same CANON KABUSHIKI KAISHA (JP) 2014-05-20 US disclosed
CN-103347841-A Phenanthrene compound and organic light emitting device using the same CANON KK 2013-10-09 CN disclosed
US-20130207096-A1 PHENANTHRENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-08-15 US disclosed
US-20130207096-A1 PHENANTHRENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-08-15 US disclosed
US-20130207096-A1 PHENANTHRENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-08-15 US disclosed
WO-2012060307-A1 PHENANTHRENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2012-05-10 WO disclosed