Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 3/20 | 0.44 |
| ▸ | S100A4 | P26447 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | EIF4E | P06730 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6930919 | 0.89 | TDP1 (0.55) | TDP1ALDH1A1MAPTPTPN1ERN1 | |
| SCHEMBL10041704 | 0.85 | TDP1 (0.57) | TDP1ALDH1A1MAPTPTPN1ERN1 | |
| SCHEMBL10041665 | 0.85 | TDP1 (0.57) | TDP1ALDH1A1MAPTPTPN1ERN1 | |
| SCHEMBL6003472 | 0.85 | ERN1 (0.52) | TDP1ALDH1A1MAPTPTPN1ERN1 | |
| SCHEMBL27547924 | 0.84 | ERN1 (0.47) | TDP1ERN1S100A4MEN1LMNA | |
| SCHEMBL31488266 | 0.82 | ERN1 (0.59) | TDP1ALDH1A1MAPTERN1S100A4 | |
| SCHEMBL2471502 | 0.82 | ALDH1A1 (0.47) | TDP1ALDH1A1ERN1S100A4MEN1 | |
| SCHEMBL13350048 | 0.82 | ERN1 (0.59) | TDP1ALDH1A1MAPTERN1S100A4 | |
| SCHEMBL546960 | 0.82 | TDP1 (0.44) | TDP1ALDH1A1ERN1S100A4MEN1 | |
| SCHEMBL1547476 | 0.82 | TDP1 (0.52) | TDP1ALDH1A1ERN1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10700289-B2 | Heterocyclic compound and organic light emitting element comprising same | LG CHEM, LTD. (KR) | 2020-06-30 | — | — | US | disclosed |
| US-10654878-B2 | Compounds of phosphinanes and azaphosphinanes, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2020-05-19 | — | — | US | disclosed |
| US-10654878-B2 | Compounds of phosphinanes and azaphosphinanes, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2020-05-19 | — | — | US | disclosed |
| US-20190031693-A1 | COMPOUNDS OF PHOSPHINANES AND AZAPHOSPHINANES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2019-01-31 | — | — | US | disclosed |
| US-20190031693-A1 | COMPOUNDS OF PHOSPHINANES AND AZAPHOSPHINANES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2019-01-31 | — | — | US | disclosed |
| US-10138260-B2 | Compounds of phosphinanes and azaphosphinanes, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2018-11-27 | — | — | US | disclosed |
| EP-3271368-B1 | NOVEL PHOSPHINANE AND AZAPHOSPHINANE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2018-10-31 | — | — | EP | disclosed |
| CN-108495857-A | New phospha cyclohexane class compound and azepine phospha cyclohexane class compound, their preparation method and the Pharmaceutical composition comprising them | 法国施维雅药厂 | 2018-09-04 | — | — | CN | disclosed |
| US-9972784-B2 | Compounds and organic electronic device using same | LG CHEM, LTD. (KR) | 2018-05-15 | — | — | US | disclosed |
| US-9972784-B2 | Compounds and organic electronic device using same | LG CHEM, LTD. (KR) | 2018-05-15 | — | — | US | disclosed |
| US-9139562-B2 | Nitrogen-containing heterocyclic compound and organic electronic device using the same | LG CHEM, LTD. (KR) | 2015-09-22 | — | — | US | disclosed |
| US-20140110694-A1 | NOVEL COMPOUNDS AND ORGANIC ELECTRONIC DEVICE USING SAME | LG CHEM, LTD. (KR) | 2014-04-24 | — | — | US | disclosed |
| US-20140110694-A1 | NOVEL COMPOUNDS AND ORGANIC ELECTRONIC DEVICE USING SAME | LG CHEM, LTD. (KR) | 2014-04-24 | — | — | US | disclosed |
| US-8368062-B2 | Nitrogen-containing heterocyclic compound and organic electronic device using the same | LG CHEM, LTD. (KR) | 2013-02-05 | — | — | US | disclosed |
| US-8368062-B2 | Nitrogen-containing heterocyclic compound and organic electronic device using the same | LG CHEM, LTD. (KR) | 2013-02-05 | — | — | US | disclosed |
| US-20120007069-A1 | NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | LG CHEM, LTD. (KR) | 2012-01-12 | — | — | US | disclosed |
| US-20120007069-A1 | NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | LG CHEM, LTD. (KR) | 2012-01-12 | — | — | US | disclosed |
| US-20110127513-A1 | NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | LG CHEM, LTD. (KR) | 2011-06-02 | — | — | US | disclosed |
| US-20110127513-A1 | NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | LG CHEM, LTD. (KR) | 2011-06-02 | — | — | US | disclosed |
| WO-2010062065-A2 | NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | 주식회사 엘지화학 (KR) | 2010-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10654878-B2 | Compounds of phosphinanes and azaphosphinanes, a process for their preparation and pharmaceutical compositions containing them | TK1, AK1, PHKA1 | TDP1 544/4885ALDH1A1 1469/4885MAPT 4054/4885 |
| US-20120007069-A1 | NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | VDAC2, VDAC1, VDAC3 | TDP1 1851/4885ALDH1A1 2949/4885MAPT 2655/4885 |
| US-10138260-B2 | Compounds of phosphinanes and azaphosphinanes, a process for their preparation and pharmaceutical compositions containing them | TK1, AK1, PHKA1 | TDP1 544/4885ALDH1A1 1469/4885MAPT 4054/4885 |
| US-20110127513-A1 | NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | VDAC2, VDAC1, VDAC3 | TDP1 1851/4885ALDH1A1 2949/4885MAPT 2655/4885 |
| US-10700289-B2 | Heterocyclic compound and organic light emitting element comprising same | CRY1, CRY2, PER2 | TDP1 4181/4885ALDH1A1 750/4885MAPT 1310/4885 |
| US-20190031693-A1 | COMPOUNDS OF PHOSPHINANES AND AZAPHOSPHINANES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AK1, TK1, PHKA1 | TDP1 558/4885ALDH1A1 1477/4885MAPT 4153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.