Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC18A2 | Q05940 | 2/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CEL | P19835 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8777913 | 0.80 | CYP19A1 (0.44) | SLC18A2 | |
| SCHEMBL8777965 | 0.80 | CYP19A1 (0.44) | SLC18A2 | |
| SCHEMBL8777909 | 0.78 | TAAR1 (0.44) | SLC18A2 | |
| SCHEMBL7636658 | 0.73 | NOS1 (0.43) | — | |
| SCHEMBL1168660 | 0.71 | NOS1 (0.44) | — | |
| SCHEMBL295542 | 0.69 | NOS1 (0.50) | — | |
| SCHEMBL1968440 | 0.69 | SLC18A2 (0.49) | SLC18A2 | |
| SCHEMBL7286965 | 0.68 | TAAR1 (0.50) | SLC18A2 | |
| SCHEMBL5214635 | 0.68 | CYP1A2 (0.50) | — | |
| SCHEMBL10707537 | 0.68 | EPHX1 (0.41) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |