SCHEMBL6003760

SCHEMBL6003760

Nc1nc(N)c(F)c(F)c1F

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
REV1 Q9UBZ9 1/20 0.30
NQO1 P15559 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20449075 0.76 LMNA (0.36) NQO1
SCHEMBL17552002 0.76 LMNA (0.36)
SCHEMBL6003429 0.74 AXL (0.30)
SCHEMBL9162427 0.74 DCPS (0.35)
SCHEMBL6409272 0.70 LMNA (0.32)
SCHEMBL6003621 0.69 NQO1 (0.30) NQO1
SCHEMBL10414868 0.69 NQO1 (0.50) NQO1
SCHEMBL2889730 0.67
SCHEMBL1565794 0.65 KHK (0.46) NQO1
SCHEMBL6602480 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107778293-B Improved preparation method of delafloxacin 鲁南制药集团股份有限公司 2023-06-16 CN claimed
CN-107778293-B Improved preparation method of delafloxacin 鲁南制药集团股份有限公司 2023-06-16 CN disclosed
US-7092608-B2 Polyimide optical materials, polyimide precursor solutions and optical waveguide elements KABUSHIKI KAISHA TOSHIBA (JP) 2006-08-15 US disclosed
US-7082244-B2 Polyimide optical materials, polyimide precursor solutions and optical waveguide elements KABUSHIKI KAISHA TOSHIBA (JP) 2006-07-25 US disclosed
US-20060159413-A1 POLYIMIDE OPTICAL MATERIALS, POLYIMIDE PRECURSOR SOLUTIONS AND OPTICAL WAVEGUIDE ELEMENTS KABUSHIKI KAISHA TOSHIBA (JP) 2006-07-20 US disclosed
US-20040197064-A1 Polyimide optical materials, polyimide precursor solutions and optical waveguide elements KABUSHIKI KAISHA TOSHIBA (JP) 2004-10-07 US disclosed