Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 1/20 | 0.50 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.50 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.50 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6004934 | 0.91 | MAPT (0.49) | KCNQ3KCNQ2KCNQ4KCNQ5ALDH1A1 | |
| SCHEMBL6005096 | 0.91 | MAPT (0.48) | KCNQ3KCNQ2KCNQ4KCNQ5ALDH1A1 | |
| SCHEMBL6004957 | 0.91 | KCNQ3 (0.55) | KCNQ3KCNQ2KCNQ4KCNQ5ALDH1A1 | |
| SCHEMBL6005020 | 0.89 | KCNQ3 (0.52) | KCNQ3KCNQ2KCNQ4KCNQ5ALDH1A1 | |
| SCHEMBL6004889 | 0.88 | THRB (0.51) | KCNQ3KCNQ2KCNQ4KCNQ5KMT2A | |
| SCHEMBL6005078 | 0.87 | KCNQ3 (0.50) | KCNQ3KCNQ2KCNQ4KCNQ5ALDH1A1 | |
| SCHEMBL6004969 | 0.85 | KCNQ3 (0.51) | KCNQ3KCNQ2KCNQ4KCNQ5ALDH1A1 | |
| SCHEMBL6004821 | 0.85 | KCNQ3 (0.48) | KCNQ3KCNQ2KCNQ4KCNQ5ALDH1A1 | |
| SCHEMBL6005471 | 0.85 | KCNQ3 (0.59) | KCNQ3KCNQ2KCNQ4KCNQ5ALDH1A1 | |
| SCHEMBL6005439 | 0.85 | KCNQ2 (0.64) | KCNQ3KCNQ2KCNQ4KCNQ5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060167087-A1 | Substituted aniline derivatives | H. LUNDBECK A/S (DK) | 2006-07-27 | — | — | US | disclosed |
| EP-1606247-A1 | SUBSTITUTED ANILINE DERIVATIVES | H. Lundbeck A/S (DK) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004080950-A1 | SUBSTITUTED ANILINE DERIVATIVES | H. LUNDBECK A/S (DK) | 2004-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167087-A1 | Substituted aniline derivatives | CYP3A43, UGT2B7, CYP3A7 | KCNQ3 2474/4885KCNQ2 2612/4885KCNQ4 3100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.