Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.46 |
| ▸ | ACP1 | P24666 | 2/20 | 0.44 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44951 | 0.88 | — | — | |
| Bicarbonate SCHEMBL10803241 | 0.86 | TSHR (0.50) | KCNH3TSHRNAPRTHSD17B10SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL892263 | 0.85 | KCNH3 (0.47) | KCNH3TSHRNAPRTHSD17B10SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6761971 | 0.85 | KCNH3 (0.47) | KCNH3TSHRNAPRTHSD17B10SMN1; SMN2 | |
| Fluoride SCHEMBL28139765 | 0.85 | PHGDH (0.46) | KCNH3TSHRNAPRTHSD17B10SMN1; SMN2 | |
| SCHEMBL28771750 | 0.85 | PHGDH (0.46) | KCNH3TSHRNAPRTHSD17B10SMN1; SMN2 | |
| Acetic Acid SCHEMBL28217523 | 0.84 | NAPRT (0.54) | TSHRNAPRTHSD17B10SMN1; SMN2MAPT | |
| Formic Acid SCHEMBL29077132 | 0.82 | ALDH1A1 (0.44) | KCNH3TSHRNAPRTHSD17B10SMN1; SMN2 | |
| SCHEMBL9620354 | 0.82 | PHGDH (0.45) | KCNH3TSHRNAPRTHSD17B10SMN1; SMN2 | |
| Sulfuric Acid SCHEMBL28377933 | 0.81 | CYP3A4 (0.44) | KEAP1ACP1TSHRSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7018426-B2 | Oxidation dye | WELLA AG (DE) | 2006-03-28 | — | — | US | disclosed |
| US-6648923-B1 | Ready to apply | WELLA AKTIENGESELLSCHAFT (DE) | 2003-11-18 | — | — | US | disclosed |
| US-6558433-B2 | Oxidation hair dye | WELLA AG (DE) | 2003-05-06 | — | — | US | disclosed |