Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | AVPR1A | P37288 | 14/20 | 0.54 |
| ▸ | AVPR2 | P30518 | 11/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3455832 | 0.92 | HSD11B1 (0.56) | HSD11B1LMNAALDH1A1MEN1HTT | |
| SCHEMBL5967739 | 0.89 | LMNA (0.60) | HSD11B1LMNAALDH1A1MEN1HTT | |
| SCHEMBL5967754 | 0.81 | ALDH1A1 (0.58) | HSD11B1LMNAALDH1A1MEN1HTT | |
| SCHEMBL3454816 | 0.81 | LMNA (0.63) | HSD11B1LMNAALDH1A1MEN1HTT | |
| SCHEMBL3455659 | 0.80 | LMNA (0.60) | HSD11B1LMNAALDH1A1MEN1HTT | |
| SCHEMBL1306648 | 0.80 | HSD11B1 (0.68) | HSD11B1LMNAALDH1A1MEN1HTT | |
| SCHEMBL1308282 | 0.78 | LMNA (0.61) | HSD11B1LMNAALDH1A1MEN1HTT | |
| SCHEMBL2895100 | 0.78 | ALDH1A1 (0.73) | HSD11B1LMNAALDH1A1MEN1HTT | |
| SCHEMBL3454763 | 0.77 | LMNA (0.58) | HSD11B1LMNAALDH1A1MEN1HTT | |
| SCHEMBL1307429 | 0.76 | LMNA (0.57) | HSD11B1LMNAALDH1A1MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615698-A2 | NEW AMIDE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | NOVO NORDISK A/S (DK) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004089470-A2 | NEW AMIDE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | NOVO NORDISK A/S (DK) | 2004-10-21 | — | — | WO | disclosed |