Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 10/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 5/20 | 0.39 |
| ▸ | KDR | P35968 | 5/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 3/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | TEK | Q02763 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzylamine SCHEMBL6004866 | 0.85 | KDR (0.46) | METAXLKDRPDGFRAPDGFRB | |
| Beclamide SCHEMBL6004229 | 0.83 | MET (0.41) | METDHODHRETAXLKDR | |
| SCHEMBL6002935 | 0.82 | SRC (0.48) | METAXLKDRPDGFRALCK | |
| SCHEMBL6004924 | 0.80 | KDR (0.57) | METRETAXLKDRPDGFRA | |
| SCHEMBL6004737 | 0.79 | SRC (0.48) | METAXLKDRPDGFRALCK | |
| SCHEMBL3895779 | 0.77 | FGFR2 (0.53) | AXLKDRPDGFRAPDGFRBSRC | |
| SCHEMBL6005288 | 0.77 | KDR (0.52) | METRETAXLKDRLCK | |
| SCHEMBL6004243 | 0.76 | SRC (0.41) | METAXLKDRPDGFRALCK | |
| SCHEMBL6004257 | 0.76 | PDPK1 (0.47) | METKDRPDGFRAPDGFRBSRC | |
| SCHEMBL6004096 | 0.76 | PDPK1 (0.47) | METKDRPDGFRAPDGFRBSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1724268-A1 | COMPOUND HAVING TGF-BETA INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-11-22 | — | — | EP | disclosed |