Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 7/20 | 0.54 |
| ▸ | KCNQ3 | O43525 | 6/20 | 0.54 |
| ▸ | KCNQ4 | P56696 | 3/20 | 0.54 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002980 | 0.93 | KCNQ2 (0.54) | KCNQ2KCNQ3KCNQ4KCNQ5ALDH1A1 | |
| SCHEMBL6005471 | 0.89 | KCNQ3 (0.59) | KCNQ2KCNQ3KCNQ4KCNQ5ALDH1A1 | |
| SCHEMBL6004798 | 0.87 | KCNQ2 (0.56) | KCNQ2KCNQ3KCNQ4KCNQ5ALDH1A1 | |
| SCHEMBL30796173 | 0.85 | KCNQ2 (0.70) | KCNQ2KCNQ3KCNQ4KCNQ5ALDH1A1 | |
| SCHEMBL3104406 | 0.85 | KCNQ2 (0.70) | KCNQ2KCNQ3KCNQ4KCNQ5ALDH1A1 | |
| SCHEMBL6005439 | 0.85 | KCNQ2 (0.64) | KCNQ2KCNQ3KCNQ4KCNQ5ALDH1A1 | |
| SCHEMBL8966006 | 0.85 | KCNQ2 (0.58) | KCNQ2KCNQ3KCNQ4KCNQ5ALDH1A1 | |
| SCHEMBL6004889 | 0.84 | THRB (0.51) | KCNQ2KCNQ3KCNQ4KCNQ5KMT2A | |
| SCHEMBL6005377 | 0.83 | MAPT (0.51) | KCNQ2KCNQ3KCNQ4KCNQ5ALDH1A1 | |
| SCHEMBL2235641 | 0.83 | KCNQ2 (0.70) | KCNQ2KCNQ3KCNQ4KCNQ5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060167087-A1 | Substituted aniline derivatives | H. LUNDBECK A/S (DK) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167087-A1 | Substituted aniline derivatives | CYP3A43, UGT2B7, CYP3A7 | KCNQ2 2612/4885KCNQ3 2474/4885KCNQ4 3100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.