Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | LAP3 | P28838 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | ADH4 | P08319 | 1/20 | 0.35 |
| ▸ | ADH7 | P40394 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6005042 | 0.93 | — | — | |
| SCHEMBL6008534 | 0.84 | — | — | |
| SCHEMBL270648 | 0.77 | MAPT (0.39) | OPRM1LAP3TP53MAPTADH1B | |
| SCHEMBL11111748 | 0.76 | MAPT (0.42) | MAPTADH1BADH1CADH1AADH4 | |
| SCHEMBL270098 | 0.76 | MAPT (0.38) | OPRM1MAPTDPP7ADH1BADH1C | |
| SCHEMBL271630 | 0.76 | ADH1B (0.50) | OPRM1TP53SPHK1MAPTADH1B | |
| SCHEMBL3026850 | 0.74 | DNM1 (0.41) | MAPTADH1BADH1CADH1AADH4 | |
| SCHEMBL277516 | 0.74 | ADH1B (0.53) | OPRM1TP53SPHK1MAPTADH1B | |
| SCHEMBL17333190 | 0.74 | MAPT (0.36) | OPRM1LAP3TP53MAPTADH1B | |
| SCHEMBL8518528 | 0.74 | ADH1B (0.53) | OPRM1TP53SPHK1MAPTADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1207161-B1 | NOVEL ISOINDOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2006-01-18 | — | — | EP | disclosed |
| US-6777410-B2 | SUCH AS 9-(2-METHOXYPHENYL)-3-(1-METHYLETHYL)-(1,3)OXAZOLO-(2,3)ISOINDOLE-2,5(3H,9H)-DIONE; DIABETES AND COMPLICATIONS; OBESITY | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-08-17 | — | — | US | disclosed |
| US-20040053923-A1 | Novel isoindole derivatives | BANYU PHARMACEUTICAL CO., LTD. | 2004-03-18 | — | — | US | disclosed |
| US-6608098-B1 | Diabetes or obesity, 2-(4-(3-isopropyl-2,5-dioxo-2,3-dihydro-1H-pyrrolo(2,1-a) isoindol-9(5H)-yl)phenoxy)-N-propylacetamide | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2003-08-19 | — | — | US | disclosed |
| EP-1207161-A1 | NOVEL ISOINDOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-05-22 | — | — | EP | disclosed |
| US-5384401-A | Aldehyde containing polymer reacted with amine chelating agent, attachment of radioactive label | NIHON MEDI-PHYSICS CO., LTD. (JP) | 1995-01-24 | — | — | US | disclosed |
| US-5077389-A | Polyformyl compound with amino-containing chelating and physiologically active compounds bonded thereto via methyleneimine or methyleneamine linkages | NIHON MEDI-PHYSICS CO., LTD. (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0111311-B1 | NON-RADIOACTIVE CARRIERS AND RADIOACTIVE DIAGNOSTIC AGENT | NIHON MEDI-PHYSICS CO., LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |
| EP-0111311-A2 | Non-radioactive carriers and radioactive diagnostic agent | NIHON MEDI-PHYSICS CO., LTD. (JP) | 1984-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053923-A1 | Novel isoindole derivatives | GPR119, SLC5A2, SLC5A1 | OPRM1 136/4885LAP3 4140/4885TP53 4143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.