Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6004296 | 0.86 | MAPT (0.56) | ALDH1A1MAPTTDP1L3MBTL1KMT2A | |
| SCHEMBL6005096 | 0.84 | MAPT (0.48) | ALDH1A1MAPTTDP1L3MBTL1KMT2A | |
| SCHEMBL6004334 | 0.84 | RAB9A (0.51) | ALDH1A1MAPTL3MBTL1KMT2AKCNQ3 | |
| SCHEMBL3104103 | 0.83 | KCNQ2 (0.56) | ALDH1A1MAPTTDP1L3MBTL1KMT2A | |
| SCHEMBL30795522 | 0.83 | KCNQ2 (0.56) | ALDH1A1MAPTTDP1L3MBTL1KMT2A | |
| SCHEMBL6004969 | 0.83 | KCNQ3 (0.51) | ALDH1A1MAPTTDP1L3MBTL1KMT2A | |
| SCHEMBL6004295 | 0.82 | KCNQ3 (0.50) | ALDH1A1MAPTTDP1L3MBTL1KMT2A | |
| SCHEMBL6004336 | 0.82 | MAPT (0.48) | ALDH1A1MAPTTDP1L3MBTL1KMT2A | |
| SCHEMBL6005377 | 0.82 | MAPT (0.51) | ALDH1A1MAPTTDP1L3MBTL1KMT2A | |
| SCHEMBL6004934 | 0.82 | MAPT (0.49) | ALDH1A1MAPTL3MBTL1KMT2AKCNQ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060167087-A1 | Substituted aniline derivatives | H. LUNDBECK A/S (DK) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167087-A1 | Substituted aniline derivatives | CYP3A43, UGT2B7, CYP3A7 | ALDH1A1 209/4885MAPT 860/4885TDP1 2762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.