Histidine

Histidine

SCHEMBL6005504

N[C@@H](Cc1c[nH]cn1)C(=O)O.[Na]

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.46
CYP3A4 P08684 2/20 0.46
CYP1A2 P05177 1/20 0.45
PKM P14618 2/20 0.42
ALPI P09923 1/20 0.42
PTGS1 P23219 1/20 0.42
XIAP P98170 1/20 0.42
GRIA2 P42262 5/20 0.40
GRIA1 P42261 4/20 0.40
GRIA3 P42263 4/20 0.40
GRIA4 P48058 4/20 0.40
HSD17B10 Q99714 2/20 0.39
KDM4E B2RXH2 2/20 0.39
MEN1 O00255 2/20 0.39
LMNA P02545 2/20 0.39
MAPT P10636 2/20 0.39
BLM P54132 2/20 0.39
PMP22 Q01453 2/20 0.39
KMT2A Q03164 2/20 0.39
HIF1A Q16665 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Histidine SCHEMBL29670800 0.98 SLC7A5 (0.45) SLC7A5CYP3A4CYP1A2PKMALPI
Histidine SCHEMBL995910 0.98 SLC7A5 (0.47) SLC7A5CYP3A4CYP1A2PKMALPI
Histidine SCHEMBL3259 0.98 SLC7A5 (0.47) SLC7A5CYP3A4CYP1A2PKMALPI
Histidine SCHEMBL388561 0.98 SLC7A5 (0.47) SLC7A5CYP3A4CYP1A2PKMALPI
Histidine SCHEMBL388563 0.98 SLC7A5 (0.47) SLC7A5CYP3A4CYP1A2PKMALPI
Histidine SCHEMBL3258 0.98 SLC7A5 (0.47) SLC7A5CYP3A4CYP1A2PKMALPI
Histidine SCHEMBL163443 0.98 SLC7A5 (0.47) SLC7A5CYP3A4CYP1A2PKMALPI
Histidine SCHEMBL18824897 0.98 SLC7A5 (0.47) SLC7A5CYP3A4CYP1A2PKMALPI
Histidine SCHEMBL163442 0.98 SLC7A5 (0.47) SLC7A5CYP3A4CYP1A2PKMALPI
Histidine SCHEMBL8080341 0.98 SLC7A5 (0.47) SLC7A5CYP3A4CYP1A2PKMALPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119613186-A Liquid suspension amino acid selenium-rich foliar fertilizer and preparation method thereof 福建省农业科学院资源环境与土壤肥料研究所 2025-03-14 CN claimed
CN-118299531-A Modified sodium supplementing nano carbon negative electrode material, preparation method thereof and sodium ion battery 四川启睿克科技有限公司 2024-07-05 CN claimed
US-20240075457-A1 METHOD OF FORMING INTEGRATED COMPOSITE COMPRISING CONDUCTIVE CARBON NETWORK SUSTAERA INC (US) 2024-03-07 US claimed
CN-114652993-B Composition and safe explosion-proof operation method 中国石油化工股份有限公司 2023-07-04 CN claimed
WO-2023119100-A1 STABLE PHARMACEUTICAL COMPOSITIONS MANKIND PHARMA LTD. (IN) 2023-06-29 WO claimed
CN-114874386-B Polymer-based ionic water-based lubricating additive and preparation method and application thereof 中国科学院兰州化学物理研究所 2023-04-04 CN claimed
CN-114874386-A Polymer-based ionic water-based lubricating additive and preparation method and application thereof 中国科学院兰州化学物理研究所 2022-08-09 CN claimed
CN-114652993-A Composition and safe explosion-proof operation method 中国石油化工股份有限公司 2022-06-24 CN claimed
CN-111185071-B Carbon dioxide absorbent and preparation method and application thereof 国家能源投资集团有限责任公司 2022-03-11 CN claimed
CN-113454111-A Antibody formulations 健玛保 2021-09-28 CN claimed
CN-113365698-A Pharmaceutical compositions comprising bispecific anti-CD 37 antibodies 健玛保控股有限公司 2021-09-07 CN claimed
CN-110944667-A Antibody-drug conjugate formulations and lyophilisations thereof 第一三共株式会社 2020-03-31 CN claimed
CN-122094705-A PTH treatment for chronic kidney disease 2026-05-26 CN disclosed
US-20250127900-A1 STABLE PHARMACEUTICAL COMPOSITIONS MANKIND PHARMA LTD. (IN) 2025-04-24 US disclosed
CN-119613186-A Liquid suspension amino acid selenium-rich foliar fertilizer and preparation method thereof 福建省农业科学院资源环境与土壤肥料研究所 2025-03-14 CN disclosed
WO-2025037213-A1 PHARMACEUTICAL FORMULATIONS OF GPR119 AGONISTS AND USES THEREOF MANKIND PHARMA LTD. (IN) 2025-02-20 WO disclosed
US-4956471-A Process for isolating and purifying amino acids AJINOMOTO COMPANY, INC. (JP) 1990-09-11 US disclosed
US-4914129-A Antihypertensive 5-amino-4-hydroxyvaleryl derivatives substituted by sulphur-containing groups CIBA-GEIGY CORPORATION (US) 1990-04-03 US disclosed
US-4889869-A ANTIALDOSTERONISM AGENTS CIBA-GEIGY CORPORATION (US) 1989-12-26 US disclosed
US-4758584-A Antihypertensive 5-amino-4-hydroxyvaleryl derivatives substituted by sulphur-containing groups CIBA-GEIGY CORPORATION (US) 1988-07-19 US disclosed