Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL317764 | 0.80 | CA12 (0.42) | CA12CA1CA9ALDH1A1ALOX15 | |
| SCHEMBL1832044 | 0.79 | ALB (0.43) | ALBCA12CA1CA9CES2 | |
| SCHEMBL317656 | 0.77 | TTR (0.44) | ALBCA12CA1CA9GAA | |
| SCHEMBL4901236 | 0.76 | TLR9 (0.49) | CA12CA1CA9GAAALDH1A1 | |
| SCHEMBL334907 | 0.76 | CA12 (0.39) | CA12CA1CA9GAAHPGD | |
| SCHEMBL6006263 | 0.75 | TSHR (0.56) | GAAHPGDALDH1A1KMT2A | |
| SCHEMBL31716917 | 0.74 | KMT2A (0.42) | ALDH1A1KMT2A | |
| SCHEMBL28755352 | 0.73 | TLR9 (0.45) | CA12CA1CA9GAAALDH1A1 | |
| SCHEMBL3678196 | 0.73 | NPC1 (0.48) | CA12CA1CA9HPGDALDH1A1 | |
| SCHEMBL30311470 | 0.72 | ALB (0.47) | ALBHPGDALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112939948-B | Novel quinazoline-containing compound, intermediate and application thereof | 苏州美诺医药科技有限公司 | 2022-05-17 | — | — | CN | disclosed |
| WO-2021115432-A1 | NOVEL QUINAZOLINE-CONTAINING COMPOUND, AND INTERMEDIATE THEREOF AND USE THEREOF | 苏州长禾药业股份有限公司 | 2021-06-17 | — | — | WO | disclosed |
| CN-112939948-A | Novel quinazoline-containing compound, intermediate and application thereof | 苏州长禾药业股份有限公司 | 2021-06-11 | — | — | CN | disclosed |
| EP-1827239-B1 | POSITRON EMISSION TOMOGRAPHY IMAGING METHOD | PURDUE RESEARCH FOUNDATION (US) | 2019-04-17 | — | — | EP | disclosed |
| EP-2452695-A2 | Positron emission tomography imaging method | Purdue Research Foundation (US) | 2012-05-16 | — | — | EP | disclosed |
| US-8093405-B2 | Formation of 18F and 19F fluoroarenes bearing reactive functionalities | UNIVERSITY OF NEWCASTLE UPON TYNE (GB) | 2012-01-10 | — | — | US | disclosed |
| EP-2310362-A1 | FORMATION OF 18F AND 19F FLUOROARENES BEARING REACTIVE FUNCTIONALITIES | University Of Newcastle-Upon Tyne (GB) | 2011-04-20 | — | — | EP | disclosed |
| WO-2009138763-A1 | FORMATION OF 18F AND 19F FLUOROARENES BEARING REACTIVE FUNCTIONALITIES | UNIVERSITY OF NEWCASTLE UPON TYNE (GB) | 2009-11-19 | — | — | WO | disclosed |
| US-20090286992-A1 | FORMATION OF 18F AND 19F FLUOROARENES BEARING REACTIVE FUNCTIONALITIES | UNIVERSITY OF NEWCASTLE UPON TYNE (GB) | 2009-11-19 | — | — | US | disclosed |
| EP-1827239-A4 | POSITRON EMISSION TOMOGRAPHY IMAGING METHOD | PURDUE RESEARCH FOUNDATION (US) | 2009-07-22 | — | — | EP | disclosed |
| US-20070276231-A1 | Positron Emission Tomography Imaging Method | PURDUE RESEARCH FOUNDATION | 2007-11-29 | — | — | US | disclosed |
| EP-1827239-A2 | POSITRON EMISSION TOMOGRAPHY IMAGING METHOD | PURDUE RESEARCH FOUNDATION (US) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006071754-A2 | POSITRON EMISSION TOMOGRAPHY IMAGING METHOD | PURDUE RESEARCH FOUNDATION (US) | 2006-07-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286992-A1 | FORMATION OF 18F AND 19F FLUOROARENES BEARING REACTIVE FUNCTIONALITIES | RARB, RARG, RARA | ALB 2282/4885CA12 316/4885CA1 638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.