SCHEMBL600723

SCHEMBL600723

COc1ccc(C=C(CC(=O)NCCO)C(=O)O)cc1

nearest known ligand 0.52

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.52
▸ MAPT P10636 3/20 0.48
▸ THRB P10828 2/20 0.48
▸ GSK3B P49841 1/20 0.43
▸ POLB P06746 2/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ ATM Q13315 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL600722 1.00 LMNA (0.52) LMNAMAPTTHRBGSK3BPOLB
SCHEMBL6656783 0.85 ALDH1A1 (0.51) —
SCHEMBL6656789 0.85 ALDH1A1 (0.51) —
SCHEMBL5799213 0.81 MAPT (0.51) LMNAMAPTTHRBGSK3BPOLB
SCHEMBL6654014 0.81 GSK3B (0.51) LMNAMAPTTHRBGSK3BPOLB
SCHEMBL6654010 0.81 GSK3B (0.51) LMNAMAPTTHRBGSK3BPOLB
SCHEMBL28509017 0.79 MAPT (0.46) LMNAMAPTTHRBGSK3BPOLB
SCHEMBL285248 0.76 MAPT (0.50) MAPTTHRBGSK3BATM
SCHEMBL6659979 0.76 MAPT (0.50) MAPTTHRBGSK3BATM
SCHEMBL8419202 0.76 MAPT (0.50) MAPTTHRBGSK3BATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10435566-B2 Particles for electrophoretic displays MERCK PATENT GMBH (DE) 2019-10-08 — — US disclosed
US-10428220-B2 Particles for electrophoretic displays MERCK PATENT GMBH (DE) 2019-10-01 — — US disclosed
EP-3233944-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2019-09-04 — — EP disclosed
EP-3234042-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2019-06-19 — — EP disclosed
EP-2393849-B1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2019-06-19 — — EP disclosed
EP-2834705-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS COMPRISING A CORE AND A RANDOM-COPOLYMER COATING MERCK PATENT GMBH (DE) 2018-12-05 — — EP disclosed
US-10126625-B2 Particles for electrophoretic displays comprising a core and a random-copolymer coating MERCK PATENT GMBH (DE) 2018-11-13 — — US disclosed
EP-2850116-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2018-04-18 — — EP disclosed
EP-2785797-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2018-03-21 — — EP disclosed
EP-2601268-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2018-03-21 — — EP disclosed
US-20110310462-A1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-12-22 — — US disclosed
US-20110306742-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-12-15 — — US disclosed
EP-2393850-A1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS Merck Patent GmbH (DE) 2011-12-14 — — EP disclosed
EP-2393851-A2 PARTICLES FOR ELECTROPHORETIC DISPLAYS Merck Patent GmbH (DE) 2011-12-14 — — EP disclosed
EP-2393848-A1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS Merck Patent GmbH (DE) 2011-12-14 — — EP disclosed
US-20110297888-A1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-12-08 — — US disclosed
WO-2010089057-A2 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2010-08-12 — — WO disclosed
WO-2010089060-A2 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2010-08-12 — — WO disclosed
WO-2010089059-A1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2010-08-12 — — WO disclosed
WO-2010089058-A1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH, (DE) 2010-08-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10435566-B2 Particles for electrophoretic displays RAB5IF, SELP, SELE LMNA 1247/4885MAPT 3084/4885THRB 4611/4885
US-20110306742-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS RAB5IF, IK, SELP LMNA 1263/4885MAPT 2386/4885THRB 4756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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