Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6009314 | 0.87 | SLC6A2 (0.50) | SLC6A2SLC6A4ALDH1A1ATMCARM1 | |
| SCHEMBL6007492 | 0.84 | SLC6A2 (0.48) | SLC6A2SLC6A4ALDH1A1ATMKDM4E | |
| SCHEMBL6008837 | 0.84 | SLC6A2 (0.56) | SLC6A2SLC6A4ALDH1A1ATMCARM1 | |
| SCHEMBL6007980 | 0.83 | CARM1 (0.52) | SLC6A2SLC6A4ALDH1A1ATMCARM1 | |
| Hydrochloric Acid SCHEMBL6007340 | 0.83 | SLC6A2 (0.55) | SLC6A2SLC6A4ALDH1A1ATMCARM1 | |
| SCHEMBL6008203 | 0.80 | SIGMAR1 (0.50) | SLC6A2SLC6A4ALDH1A1ATMKDM4E | |
| Hydrochloric Acid SCHEMBL6009473 | 0.74 | GRIN2D (0.53) | ALDH1A1CARM1PRMT6HTTCCR3 | |
| SCHEMBL6007453 | 0.71 | ALDH1A1 (0.49) | SLC6A2SLC6A4ALDH1A1ATMCARM1 | |
| SCHEMBL9750911 | 0.70 | KMT2A (0.81) | ALDH1A1ATMGAAMAPTDRD4 | |
| SCHEMBL5790284 | 0.70 | SLC6A2 (0.48) | SLC6A2SLC6A4CCR3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078537-B2 | Phenylalkyl diamine and amide analogs | SK CORPORATION (KR) | 2006-07-18 | — | — | US | claimed |
| US-7078537-B2 | Phenylalkyl diamine and amide analogs | SK CORPORATION (KR) | 2006-07-18 | — | — | US | disclosed |