Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.50 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.46 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6008834 | 0.90 | SIGMAR1 (0.56) | SIGMAR1NPFFR1NPFFR2CCR3HTT | |
| SCHEMBL6007492 | 0.85 | SLC6A2 (0.48) | SIGMAR1CCR3HTTDRD4SLC6A2 | |
| SCHEMBL6007352 | 0.80 | SLC6A2 (0.53) | SIGMAR1CCR3HTTDRD4SLC6A2 | |
| SCHEMBL6009314 | 0.80 | SLC6A2 (0.50) | SIGMAR1CCR3HTTDRD4SLC6A2 | |
| SCHEMBL6008676 | 0.79 | CCR3 (0.61) | SIGMAR1NPFFR1NPFFR2CCR3SLC6A2 | |
| SCHEMBL6009258 | 0.76 | SIGMAR1 (0.54) | SIGMAR1NPFFR1NPFFR2HTTSLC6A2 | |
| SCHEMBL6008837 | 0.75 | SLC6A2 (0.56) | SIGMAR1CCR3HTTDRD4SLC6A2 | |
| SCHEMBL6007980 | 0.74 | CARM1 (0.52) | SIGMAR1NPFFR1NPFFR2CCR3HTT | |
| Hydrochloric Acid SCHEMBL6007340 | 0.74 | SLC6A2 (0.55) | SIGMAR1CCR3HTTDRD4SLC6A2 | |
| SCHEMBL6008656 | 0.74 | ALDH1A1 (0.47) | SIGMAR1NPFFR1NPFFR2CCR3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078537-B2 | Phenylalkyl diamine and amide analogs | SK CORPORATION (KR) | 2006-07-18 | — | — | US | disclosed |