SCHEMBL9119115

SCHEMBL9119115

Nc1ccc2c(ccc3cc(C(=O)O)ccc32)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.53
KDM4E B2RXH2 6/20 0.46
SMYD3 Q9H7B4 1/20 0.45
GRIN2D O15399 1/20 0.45
GRIN2A Q12879 1/20 0.45
GRIN2C Q14957 1/20 0.45
MAPT P10636 6/20 0.44
ALDH1A1 P00352 5/20 0.44
HPGD P15428 4/20 0.44
PLAU P00749 1/20 0.44
TDP1 Q9NUW8 4/20 0.43
RECQL P46063 3/20 0.43
POLB P06746 3/20 0.43
GAA P10253 3/20 0.43
CSNK2A2 P19784 1/20 0.43
CSNK2B P67870 1/20 0.43
CSNK2A1 P68400 1/20 0.43
CSNK2A3 Q8NEV1 1/20 0.43
NPC1 O15118 1/20 0.43
MITF O75030 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29398350 0.90 KDM4E (0.55) PTPN1KDM4ESMYD3MAPTALDH1A1
SCHEMBL100233 0.90 KDM4E (0.55) PTPN1KDM4ESMYD3MAPTALDH1A1
SCHEMBL437116 0.88 KDM4E (0.48) PTPN1KDM4ESMYD3MAPTALDH1A1
SCHEMBL7088722 0.88 PTPN1 (0.64) PTPN1KDM4EGRIN2DGRIN2AGRIN2C
SCHEMBL9121653 0.86 ALDH1A1 (0.54) PTPN1KDM4ESMYD3MAPTALDH1A1
SCHEMBL6865178 0.86 ALDH1A1 (0.54) PTPN1KDM4ESMYD3MAPTALDH1A1
SCHEMBL28624473 0.84 KDM4E (0.57) PTPN1KDM4ESMYD3MAPTALDH1A1
SCHEMBL6007565 0.79 PTPN1 (0.51) PTPN1KDM4EGRIN2DGRIN2AGRIN2C
SCHEMBL15960260 0.78 ALDH1A1 (0.70) PTPN1KDM4EGRIN2DGRIN2AGRIN2C
SCHEMBL2469662 0.78 ALDH1A1 (0.70) PTPN1KDM4EGRIN2DGRIN2AGRIN2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5391699-A Containing an aromatic amine carboxylate, heat resistance BRIDGESTONE CORPORATION (JP) 1995-02-21 US claimed
EP-0571095-A2 Polyester copolymer and process for the production of the same BRIDGESTONE CORPORATION (JP) 1993-11-24 EP claimed
US-5391699-A Containing an aromatic amine carboxylate, heat resistance BRIDGESTONE CORPORATION (JP) 1995-02-21 US disclosed
EP-0571095-A2 Polyester copolymer and process for the production of the same BRIDGESTONE CORPORATION (JP) 1993-11-24 EP disclosed